For increasing sites and an ordered nonnegative normalized B-spline basis, the matrix is a totally nonnegative matrix. One way to see the minors' signs is knot insertion. Each inserted knot changes coefficients by with , using the standard constant endpoint pieces. This is a nonnegative rectangular bidiagonal map, whose minors are nonnegative. Products preserve that property by the Cauchy–Binet formula. Insert each site to full knot multiplicity; a suitable refined coefficient is then the value . Thus collocation is an ordered row submatrix of the refinement map, and has nonnegative minors. The strict support conditions give invertibility by the Schoenberg–Whitney theorem; its inverse has the checkerboard inverse of a totally nonnegative matrix sign pattern.

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