Two-hybrid screening is a molecular biology technique used to investigate protein-protein interactions within cells. It is particularly useful for identifying and characterizing interactions between different proteins, which is crucial for understanding cellular processes, signaling pathways, and the molecular mechanisms underlying various biological functions.
Viability PCR (v-PCR) is a molecular biology technique used to differentiate live cells from dead cells in a sample, particularly in microbial analysis. This method leverages the polymerase chain reaction (PCR) to amplify genetic material from viable organisms while selectively excluding the genetic material from non-viable (dead) cells.
Zfp82, or zinc finger protein 82, is a member of the zinc finger protein family, which is characterized by the presence of zinc finger motifs. These motifs are specialized structural domains that can interact with DNA, RNA, or proteins, functioning primarily as transcription factors that regulate gene expression. The Zfp82 protein is involved in various biological processes, including development, cell differentiation, and possibly in the regulation of hormonal signaling.
Zinc finger protein 112 (ZFP112) is a member of the zinc finger protein family, which is characterized by the presence of zinc-finger domains that allow these proteins to bind to DNA, RNA, or other proteins. Zinc finger proteins play a crucial role in various biological processes, including gene regulation, signal transduction, and developmental processes. ZFP112 has been implicated in several biological functions, one of which is its potential role in the regulation of gene expression during development.
Zinc finger protein 180 (ZNF180) is a member of the zinc finger protein family, which is characterized by the presence of zinc finger motifs that allow these proteins to bind to DNA, RNA, or other proteins. Zinc finger proteins play significant roles in various biological processes, including transcription regulation, cell signaling, and development.
Capped trigonal prismatic molecular geometry is a specific arrangement of atoms in a molecule where there is a central atom surrounded by additional atoms or groups in a particular three-dimensional configuration. In this geometry, the central atom is at the center of a trigonal prism, and additional atoms or groups are added "cap" the top and bottom faces of the prism.
Coordination number refers to the number of ligand atoms or ions that are directly bonded to a central atom or ion in a coordination complex. It is an important concept in coordination chemistry and helps in understanding the structure and stability of coordination compounds. For example, in a metal complex such as [Co(NH₃)₆]³⁺, the cobalt ion (Co³⁺) is surrounded by six ammonia (NH₃) ligands.
Dodecahedral molecular geometry refers to a specific arrangement of atoms in a molecule that resembles the shape of a dodecahedron, which is a polyhedron with twelve flat faces (usually pentagonal). In terms of molecular geometry, a dodecahedral arrangement typically involves a central atom surrounded symmetrically by twelve other atoms or groups. In chemistry, dodecahedral geometry is not among the most common shapes seen in small molecules or simple coordination complexes.
The Journal of Molecular Structure is a scientific journal that publishes research articles, reviews, and other content related to topics in molecular structure and related fields. It is particularly focused on the study of molecular organization, molecular interactions, and the structural aspects of chemical compounds.
LCP theory refers to the **Linear Complementarity Problem** (LCP), a mathematical framework used primarily in optimization and mathematical programming. The LCP provides a way to describe and analyze systems that can be represented through inequalities and complementarity conditions. The LCP can be formally stated as follows: Given a matrix \( M \) and a vector \( q \), find vectors \( z \) and \( w \) such that: 1. \( z = Mx + q \) 2.
Pentagonal planar molecular geometry refers to a specific arrangement of atoms in a molecule where five atoms or groups are arranged around a central atom in a planar configuration. In this geometry, the bond angles between the adjacent atoms are approximately 108 degrees, which allows for a symmetrical distribution around the central atom. This molecular geometry is often associated with transition metal complexes, particularly those with a coordination number of 5, where a central metal atom can coordinate to five ligands.
Pentagonal pyramidal molecular geometry refers to the shape of a molecule in which a central atom is surrounded by five atoms or groups of atoms at the base of a pyramid and one additional atom or group at the apex, resulting in a five-sided base with a single atom above it. This configuration is characterized by the following: 1. **Coordination Number**: The central atom is coordinated to a total of six atoms or groups.
HTR-10, or High-Temperature Gas-cooled Reactor Project 10, is a modular high-temperature gas-cooled reactor (HTGR) designed in China. It is notable for its use of helium as a coolant and its ability to operate at high temperatures, which makes it suitable for various applications, including electricity generation and process heat for industrial uses. The HTR-10 has a thermal power output of around 10 megawatts and serves as a prototype for larger HTGR designs.
S/2004 S 37 is a small natural satellite (moon) of Saturn. It was discovered in 2004 and is classified as one of Saturn's many irregular moons. Irregular moons typically have eccentric orbits that are more distant from their planet compared to regular moons. S/2004 S 37 is relatively small and has an uncertain orbit, making it difficult to study in detail.
Cubic harmonics are a mathematical generalization of spherical harmonics. While traditional spherical harmonics are used primarily in problems with spherical symmetry (like those in quantum mechanics, gravitation, and electromagnetism), cubic harmonics expand this concept to three-dimensional cubes or cubic geometries. In more technical terms, cubic harmonics can represent functions defined on a cube (or in cubic coordinates) much like how spherical harmonics represent functions defined on the surface of a sphere.
An ultrafilter is a mathematical concept that arises in the field of set theory and topology, particularly in the context of ordered sets and Boolean algebras. Here's an overview of what an ultrafilter is: 1. **Definition**: An ultrafilter on a set \( X \) is a maximal filter, which is a collection of subsets of \( X \) that satisfies certain properties: - It is non-empty.
Localized molecular orbitals (LMOs) are a concept in quantum chemistry and molecular orbital theory used to describe the electron distribution in molecules. Unlike delocalized molecular orbitals, which spread over several atoms and can be seen in conjugated systems or in systems with extensive pi bonding, LMOs are more confined to specific regions or atoms within a molecule.
The Datar–Mathews method is a numerical approach for valuing real options, particularly useful in situations involving investment decisions with uncertainty and the flexibility to defer, expand, or abandon projects. This method is frequently applied in finance and economics to assess the value of options related to real assets—such as the option to delay investment in a project or the option to expand operations.
A stochastic investment model is an approach used in finance and economics to account for uncertainty and randomness in the investment process. Unlike deterministic models, which assume that future outcomes can be predicted with certainty given a specific set of initial conditions, stochastic models incorporate variability and randomness in various factors that affect investment performance. ### Key Features of Stochastic Investment Models: 1. **Random Variables**: Stochastic models often use random variables to represent uncertain outcomes, such as stock prices, interest rates, and economic indicators.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either https://OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact