This is a really good project. So fun to play around with. Low level IO part only like drawing to screen and handling keyboard inputs.
Ciro Santilli has:
Does not have any non-trivial normal subgroup.
And therefore, going back to our intuition that due to the fundamental theorem on homomorphisms there is one normal group per homomorphism, a simple group is one that has no non-trivial homomorphisms.
Simplicity is the ultimate sophistication by 
Ciro Santilli 35 Updated 2025-04-18 +Created 1970-01-01
Ciro Santilli 35 Updated 2025-04-18 +Created 1970-01-01By Da Vinci: www.goodreads.com/quotes/9010638-simplicity-is-the-ultimate-sophistication-when-once-you-have-tasted
There are infinitely many variants across the ages:
- by Blaise Pascal
- by Albert Einstein
Make everything as simple as possible, but no simpler
- by Antoine de Saint-Exupéry
Perfection is achieved, not when there is nothing more to add, but when there is nothing left to take away
- KISS principle
Because Ciro's a software engineer, and he's done enough staring in computers for a lifetime already, and he believes in the power of Git, he didn't pay much attention to this part ;-)
According to the eLife paper, the code appears to have been uploaded to: github.com/d-j-k/puntseq. TODO at least mention the key algorithms used more precisely.
Ciro can however see that it does present interesting problems!
Because it was necessary to wait for 2 days to get our data, the workshop first reused sample data from previous collections done earlier in the year to illustrate the software.
First there is some signal processing/machine learning required to do the base calling, which is not trivial in the Oxford Nanopore, since neighbouring bases can affect the signal of each other. This is mostly handled by Oxford Nanopore itself, or by hardcore programmers in the field however.
After the base calling was done, the data was analyzed using computer programs that match the sequenced 16S sequences to a database of known sequenced species.
This is of course not just a simple direct string matching problem, since like any in experiment, the DNA reads have some errors, so the program has to find the best match even though it is not exact.
The PuntSeq team would later upload the data to well known open databases so that it will be preserved forever! When ready, a link to the data would be uploaded to: www.puntseq.co.uk/data
This theorem roughly states that states that for every quantum algorithm, once we reach a certain level of physical error rate small enough (where small enough is algorithm dependant), then we can perfectly error correct.
This algorithm provides the conceptual division between noisy intermediate-scale quantum era and post-NISQ.
www.youtube.com/watch?v=-jIZ3bH-rAE "Illuminating biology at the nanoscale and systems scale using single-molecule and super-resolution imaging" by Xiaowei Zhuang (2017)
This is where they moved the Chicago Pile-1 after they decided it might be a bad idea to run highly experimental nuclear reactions right in the middle of one of the most populous cities of the United States.
So more precisely, it is a continuation of the Metallurgical Laboratory.
Ciro Santilli maintains that they chose the site because the name is so cool. Wikipedia says it is derived from the Forest of Argonne, maybe it even shared etymology with the element argon.
WTF is a skew? "Antisymmetric" is just such a better name! And it also appears in other definitions such as antisymmetric multilinear map.
Some of Feynman's key characteristics are:
- obsession with understanding the experiments well, see also Section "How to teach and learn physics"
- when doing more mathematical stuff, analogous obsession about starting with a concrete example and then generalizing that into the theory
- liked to teach others. At Surely You're Joking, Mr. Feynman for example he mentions that one key problem of the Institute for Advanced Study is that they didn't have to teach, and besides that making you feel useless when were not having new ideas, it is also the case that student's questions often inspire you to look again in some direction which sometimes happens to be profitableHe hated however mentoring others one to one, because almost everyone was too stupid for him
- interest in other natural sciences, and also random art and culture (and especially if it involves pretty women)
Some non-Physics related ones, mostly highlighted at Genius: Richard Feynman and Modern Physics by James Gleick (1994):
- Feynman was a huge womanizer during a certain period of his life
- he hated pomp, going as far as seeming uneducated to some people in the way he spoke, or going out of his way to look like that. This is in stark contrast to "rivals" Murray Gell-Mann and Julian Schwinger, who were posh/snobby.
Even Apple thinks so according to their Think different campaign: www.feynman.com/fun/think-different/
quantum electrodynamics lectures:
Feynman was apparently seriously interested/amused by computer:
- Video "Los Alamos From Below by Richard Feynman (1975)" see description for the human emulator
- quantum computers as experiments that are hard to predict outcomes was first attributed to Feynman
- www.youtube.com/watch?v=EKWGGDXe5MA Richard Feynman Computer Heuristics Lecture (1986)
Two official websites?
- www.richardfeynman.com/ this one has clearly superior scientific information.
- www.feynman.com/
In 1948 he published his reworking of classical quantum mechanics in terms of the path integral formulation: journals.aps.org/rmp/abstract/10.1103/RevModPhys.20.367 Space Time Approach to nonrelativistic quantum mechanics (paywalled 2021)
Pinned article: ourbigbook/introduction-to-the-ourbigbook-project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.
Figure 3. Visual Studio Code extension installation.
Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. 
- Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact