In the context of wave-like equations, an open-boundary condition is one that "lets the wave go through without reflection".
This condition is very useful when we want to simulate infinite domains with a numerical method. Ciro Santilli wants to do this all the time when trying to come up with demos for his physics writings.
Here are some resources that cover such boundary conditions:
- www.asc.tuwien.ac.at/~arnold/pdf/graz/graz.pdf lots of slides
- hplgit.github.io/wavebc/doc/pub/._wavebc_cyborg002.html mentions them and gives a 1D formula. It mentions that things get complicated in 2D and 3D TODO why.The other page: hplgit.github.io/wavebc/doc/pub/._wavebc_cyborg003.html shows solution demos.
How to use an Oxford Nanopore MinION to extract DNA from river water and determine which bacteria live in it Conclusions Updated 2025-05-21 +Created 1970-01-01
- against all odds, the experiment worked and we got DNA out of the water, despite a bunch of non-bio newbs actively messing with random parts of the experiment
- PuntSeq and Biomakespace people, and all those tho do scientific outreach, are awesome!
- biology is hard
- creating insanely media rich articles like this is also hard, but the following helped enormously:
- Wikimedia Commons to store large media files out of Git
- Asciidoctor extensions to easily include those media files. The lessons learnt in this article were then an important motivation for Ciro's OurBigBook Markup, to which this article was later migrated.
- Nomacs to give Google Photos photos meaningful names and to edit people's faces out of pictures ;-)
- some scientific Wikipedia pages may or may not have been edited with better pictures during the course of writing this article
How to use an Oxford Nanopore MinION to extract DNA from river water and determine which bacteria live in it DNA extraction Updated 2025-05-21 +Created 1970-01-01
What happens when the underdogs get together and try to factor out their efforts to beat some evil dominant power, sometimes victoriously.
Or when startups use the cheapest stuff available and randomly become the next big thing, and decide to keep maintaining the open stuff to get features for free from other companies, or because they are forced by the Holy GPL.
Open source frees employees. When you change jobs, a large part of the specific knowledge you acquired about closed source a project with your blood and tears goes to the trash. When companies get bought, projects get shut down, and closed source code goes to the trash. What sane non desperate person would sell their life energy into such closed source projects that could die at any moment? Working on open source is the single most important non money perk a company can have to attract the best employees.
Open source is worth more than the mere pragmatic financial value of not having to pay for software or the ability to freely add new features.
Its greatest value is perhaps the fact that it allows people study it, to appreciate the beauty of the code, and feel empowered by being able to add the features that they want.
And "can reverse engineer the undocumented GPU hardware APIs", Ciro would add.
While software is the most developed open source technology available in the 2010's, due to the "zero cost" of copying it over the Internet, Ciro also believes that the world would benefit enormously from open source knowledge in all areas on science and engineering, for the same reasons as open source.
Evil company that desecrated the beauty created by Sun Microsystems, and was trying to bury Java once and or all in the 2010's.
Their database is already matched by open source e.g. PostgreSQL, and ERP and CRM specific systems are boring.
Oracle basically grew out of selling one of the first SQL implementations in the late 70's, and notably to the United States Government and particularly the CIA. They did deliver a lot of value in those early pre-internet days, but now open source is and will supplant them entirely.
How to use an Oxford Nanopore MinION to extract DNA from river water and determine which bacteria live in it Experiment background Updated 2025-05-21 +Created 1970-01-01
PuntSeq is a side project led by a few University of Cambridge PhDs that aims to determine which bacteria are present in the River Cam.
In July 2019, the PuntSeq team got together with the awesome Cambridge Biomakespace, an awesome biology makerspace open to all, to create a two day science outreach activity showing their procedures.
The data collected in this experiment, together with other collection sessions done by the organizers actually led to a publication on eLife: elifesciences.org/articles/61504 "Freshwater monitoring by nanopore sequencing" by Lara Urban et al. (2021), so it is awesome to see that were are actual being part of "real science".
Ciro knows nothing about biology, but since he is very curious about it, he jumped at this opportunity, and decided to document things as well as his limited knowledge would allow.
All participants chipped in some money to help cover the experiment's costs. Ciro suspects that this activity was done partially to help crowdfund the experiment, but it was a worthy investment!
The impressions you get from the experiment as a software engineer will be:
- OMG, this is so labour intensive, why haven't they automated this
- OMG, this is frightening, all the 8 hours of work I've just done are present in that tiny plastic tube
- Amazing! Look at that apparatus! And the bio people are like: I've used this a million times, it's cheap and every lab has one, just work faster and don't break you piece of junk!
How to use an Oxford Nanopore MinION to extract DNA from river water and determine which bacteria live in it Fisher Scientific UVP LM-26E Benchtop 2UV Transilluminator Updated 2025-05-21 +Created 1970-01-01
www.bidspotter.com/en-us/auction-catalogues/bscsur/catalogue-id-bscsur10011/lot-c6605b41-1a14-40e5-a255-a5c5000866e0 (archive) Cannot exact same product on official website, but here is a similar one: www.fishersci.co.uk/shop/products/lm-26-2uv-transilluminator/12382038 (archive).
Cool data embedded in the Bitcoin blockchain Ordinal ruleset inscription Updated 2025-05-21 +Created 1970-01-01
Ordinals are inscriptions created with the protocol described at: docs.ordinals.com/inscriptions.html The protocol was designed by developer Casey Rodarmor, and shares a few similarities with the AtomSea & EMBII protocol.
The protocol also includes a way to have ownership over inscriptions, effectively creating an NFT system on top of the bitcoin blockchain. AtomSea & EMBII also already had such a system however. In either case, Ciro Santilli couldn't give less of a fuck about who owns some random publicly viewable digital asset.
For whatever reason, orinals became extremelly popular compared to the AtomSea & EMBII format, leading to millions os inscriptions, and 10k+ images as of block 830k. They also started to take up a substatial portion of the available block space.
This in turn led to a lot of child porn rediscussion, and people linking back to this page to view earlier inscriptions: incoming links.
Unfortunately, unlike AtomSea & EMBII and even cryptograffiti.info uploads, most ordinals are designed to be just souless bulk collectibles, as with as much artistic merit as any random collectible card set or postage stamps you may find at a newpaper stall. To make things worse many of them are likely algorithmically generated. Eternal September had truly arrived to the Bitcoin blockchain. As a result, machine learning would be almost essential in order to find interesting uploads amidst such bulk.
Ordinal #0
. This is the first ordinal ruleset inscription: ordinals.com/inscription/6fb976ab49dcec017f1e201e84395983204ae1a7c2abf7ced0a85d692e442799i0. It was made on block 767430 (2022-12-14).The
i0
at the end of the URL above means "inscription 0". This is because a single transaction can have multiple inscriptions.The ordinals also started taking up large portions of the Bitcoin blockchain:
Apparently the "Taproot" Bitcoin update made it easier to upload image-sized data once again, which had become prohibitively expensive 2023 and much earlier:
- protos.com/did-taproot-ruin-bitcoin-with-nft-inscriptions-of-monkey-jpegs/
- ordinals.com/ appears to index some types of ordinals
Bibliography:
- blocktelegraph.io/parent-child-bitcoin-inscriptions/ parent-child relationshipsi are possible between two ordinals
- ordinals.com/
- bitcoin.stackexchange.com/questions/117018/understanding-how-ordinals-work-with-the-bitcoin-blockchain-what-is-exactly-sto
- bitcoin.stackexchange.com/questions/118405/read-ordinal-transaction-data
- bitcoin.stackexchange.com/questions/118247/can-someone-explain-the-byte-composition-of-an-inscription-reveal-transaction
- nftnow.com/guides/bitcoin-nfts-most-notable-ordinals-inscriptions/
Where blog is taken in a wide sense, including e.g. Medium, WordPress, Facebook, Twitter, etc., etc.
The main shortcoming of blogs is the lack of topic convergence across blogs. Each blog is a moderated castle. So who is the best user for a given topic, or the best content for a given tag, across the entire website?
The only reasonable free material we have for advanced subjects nowadays are university lecture notes.
While some of those are awesome, when writing a large content, no one can keep quality high across all sections, there will always be knowledge that you don't have which is enlightening. And Googlers are more often than not interested only in specific sections of your content.
Our website aims to make smaller subjects vertically curated across horizontal single author tutorials.
MIT calculus course UCLA calculus course
* Calculus <---> * Calculus
* Limit <---> * Limit
* Limit of a function
* Limit of a series <---> * Limit of a series
* Derivative <---> * Derivative
* L'Hôpital's rule
* Integral <---> * Integral
Some more links:
- prose.sh/ multiblog, the only feature is easy of publishing from CLI
Start with consulting for universities to get some cash flowing.
Help teachers create perfect courses.
Choose a domain of knowledge, generate perfect courses for it, and find all teachers of the domain in the world who are teaching that and help them out.
Then expand out to other domains.
TODO: which domain of knowledge should we go for? The more precise the better.
- maths is perfect because it "never" changes. But does not make money.
- computer science might be good, e.g. machine learning.
- always upvote questions you care about, to increase the probability that they will get answered
- never upvote other people's answers unless you might gain from it somehow, otherwise you are just giving other high reputation users more reputation relative to you
- only mark something to close or as a duplicate if it will bring you some advantage, because closing things creates enemies, especially if the OP has a high profileOne example advantage is if you have already answered the question (and the duplicate as well in case of duplicates), because this will prevent competitors from adding new better answers to overtake you.
- protect questions you've answered whenever someone with less than 10 reputation answers it with a bad answer, to prevent other good contributors from coming along and beating you
- when you find a duplicate pool answer every question with similar answers.Alter each answer slightly to avoid the idiotic duplicate answer detector.If one of the question closes, it is not too bad, as it continues netting you to upvotes, and prevents new answers from coming in.
- follow on Twitter/RSS someone who comments on the top features of new software releases. E.g. for Git, follow GitHub on Twitter, C++ on Reddit. Then run back to any question which has a new answer.
- always upvote the question when you answer it:
- the more upvotes, more likely people are to click it.
- the OP is more likely to see your answer and feel good and upvote you
- if a niche question only has few answers and you come with a good one, upvote the existing ones by other high profile users.This may lead to them upvoting or liking you.
- always upvote comments that favor you:
- "I like this answer!" on your answers
- "also look at that question" when you have answered that question
- if you answer a question by newbie without 15 reputation, find their other questions if any and upvote them, so that the OP can upvote your answer in addition to just accepting
- if a question has 50 million answers and you answer it (often due to a new feature), make a comment on the question pointing to your answer
- if you get a downvote, always leave a comment asking why. It is not because you care about their useless opinion, but because other readers might see the comment, feel sorry for you, and upvote.
- ask any questions under a separate anonymous accounts. Because:
- intelligent people are born knowing, and don't ever ask any questions, so that would hurt your reputation
- downvoting questions does not take 1 reputation away from the downvoter, and so it greatly opens the door for your opponents to downvote you without any cost.
China stuff is mentioned at: cirosantilli.com/china-dictatorship/bitcoin-blockchain.
If Ciro Santilli were to write a book about quantum mechanics as of 2020 (before OurBigBook.com went live), he would upload an OurBigBook Markup website to GitHub Pages.
But there is one major problem with that: the entry barrier for new contributors is very large.
If they submit a pull request, Ciro has to review it, otherwise, no one will ever see it.
Our amazing website would allow the reader to add his own example of, say, The uncertainty principle, whenever they wants, under the appropriate section.
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