Epyc Updated 2025-07-16
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How to convert
async to sync in JavaScript Updated 2025-07-16God, it's impossible! You just have to convert the entire fucking call stack all the way up to async functions. It could mean refactoring hundreds of functions.
To be fair, there is a logic to this, if you put yourself within the crappiness of the JavaScript threading model. And Python is not that much better with its Global Interpreter Lock.
The problem is that async was introduced relatively late, previously we just had to use infinitely deep callback trees, which was worse:compared to the new infinitely more readable:But now we are in an endless period of transition between both worlds.
myAsync().then(ret => myAsync2(ret).then(ret2 => myAsync3(re3)))ret = await myAsync()
ret2 = await myAsync2(ret)
ret3 = await myAsync3(ret3)It is also worth mentioning that callbacks are still inescapable if you really want to fan out into a non-linear dependency graph, usually with
Promise.all:await Promise.all([
myAsync(1).then(ret => myAsync2(ret)),
myAsync(2).then(ret => myAsync2(ret)),
])Bibliography:
- stackoverflow.com/questions/21819858/how-to-wrap-async-function-calls-into-a-sync-function-in-node-js-or-javascript
- stackoverflow.com/questions/9121902/call-an-asynchronous-javascript-function-synchronously
- stackoverflow.com/questions/47227550/using-await-inside-non-async-function
- stackoverflow.com/questions/43832490/is-it-possible-to-use-await-without-async-in-js
- stackoverflow.com/questions/6921895/synchronous-delay-in-code-execution
And then, after many many hours of this work, you might notice that the new code is way, way way slower than before, because making small functions
async has a large performance impact: madelinemiller.dev/blog/javascript-promise-overhead/. Real world case with a 4x slowdown: github.com/ourbigbook/ourbigbook/tree/async-slow.Anyways, since you Googled here, you might as well learn the standard pattern to convert callbacks functions into async functions using a promise: stackoverflow.com/questions/4708787/get-password-from-input-using-node-js/71868483#71868483
async function Teletubbies meme
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Similar to a college, but led by religious denomination leaders rather than fellows.
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E. Coli Whole Cell Model by Covert Lab Install and first run Updated 2025-07-16
At 7e4cc9e57de76752df0f4e32eca95fb653ea64e4 you basically need to use the Docker image on Ubuntu 21.04 due to pip breaking changes... (not their fault). Perhaps pyenv would solve things, but who has the patience for that?!?!
The Docker setup from README does just work. The image download is a bit tedius, as it requires you to create a GitHub API key as described in the README, but there must be reasons for that.
Once the image is downloaded, you really want to run is from the root of the source tree:This mounts the host source under The meaning of each of the analysis commands is described at Section "Output overview".
sudo docker run --name=wcm -it -v "$(pwd):/wcEcoli" docker.pkg.github.com/covertlab/wholecellecolirelease/wcm-full/wcEcoli, so you can easily edit and view output images from your host. Once inside Docker we can compile, run the simulation, and analyze results with:make clean compile &&
python runscripts/manual/runFitter.py &&
python runscripts/manual/runSim.py &&
python runscripts/manual/analysisVariant.py &&
python runscripts/manual/analysisCohort.py &&
python runscripts/manual/analysisMultigen.py &&
python runscripts/manual/analysisSingle.pyAs a Docker refresher, after you stop the container, e.g. by restarting your computer or running
sudo docker stop wcm, you can get back into it with:sudo docker start wcm
sudo docker run -it wcm bashrunscripts/manual/runFitter.py takes about 15 minutes, and it generates files such as reconstruction/ecoli/dataclasses/process/two_component_system.py (related) which is required to run the simulation, it is basically a part of the build.runSim.py does the main simulation, progress output contains lines of type:Time (s) Dry mass Dry mass Protein RNA Small mol Expected
(fg) fold change fold change fold change fold change fold change
======== ======== =========== =========== =========== =========== ===========
0.00 403.09 1.000 1.000 1.000 1.000 1.000
0.20 403.18 1.000 1.000 1.000 1.000 1.000 2569.18 783.09 1.943 1.910 2.005 1.950 1.963
Simulation finished:
- Length: 0:42:49
- Runtime: 0:09:13 There are unlisted articles, also show them or only show them.