Some of the earlier computers of the 20th centure were analog computers, not digital.
At some point analog died however, and "computer" basically by default started meaning just "digital computer".
As of the 2010's and forward, with the limit of Moore's law and the rise of machine learning, people have started looking again into analog computing as a possile way forward. A key insight is that huge floating point precision is not that crucial in many deep learning applications, e.g. many new digital designs have tried 16-bit floating point as opposed to the more traditional 32-bit minium. Some papers are even looking into 8-bit: dl.acm.org/doi/10.5555/3327757.3327866
As an example, the Lightmatter company was trying to implement silicon photonics-based matrix multiplication.
A general intuition behind this type of development is that the human brain, the holy grail of machine learning, is itself an analog computer.
TODO who owns it? Are they reliable?
- transaction hex data: blockchain.info/tx/930a2114cdaa86e1fac46d15c74e81c09eee1d4150ff9d48e76cb0697d8e1d72?format=hex
- disassembled transaction as JSON: blockchain.info/tx/930a2114cdaa86e1fac46d15c74e81c09eee1d4150ff9d48e76cb0697d8e1d72?format=json
- block by height:
This helper dumps a transaction JSON to a binary:
bitcoin-tx-out-scripts() (
# Dump data contained in out scripts. Remove first 3 last 2 bytes of
# standard transaction boilerplate.
h="$1"
echo curl "https://blockchain.info/tx/${h}?format=json" |
jq '.out[].script' tmp.json |
sed 's/"76a914//;s/88ac"//' |
xxd -r -p > "${h}.bin"
)
None known as of 2020.
But it's not something that he would do himself, unless under extreme cases.
English translation of papers that include the original Quantization as an Eigenvalue Problem by Schrödinger (1926).
Published on Nature at www.nature.com/articles/122990a0 and therefore still paywalled there as of 2023, it's ridiculous.
In 2024 it will fall into the public domain in the US.
- www.cell.com/cell/fulltext/S0092-8674(15)00568-1 2015. Using Genome-scale Models to Predict Biological Capabilities. Edward J. O'Brien, Jonathan M. Monk, Bernhard O. Palsson.
- www.quora.com/What-are-some-good-books-on-Escherichia-Coli-E-Coli
Size: 1-2 micrometers long and about 0.25 micrometer in diameter, so:
2 * 0.5 * 0.5 * 10e-18
and thus 0.5 micrometer square.Reference strain: E. Coli K-12 MG1655.
Genome:
- 4k genes
- 5 Mbps
- www.ncbi.nlm.nih.gov/genome/167
wget ftp://ftp.ncbi.nlm.nih.gov/genomes/all/GCF/000/005/845/GCF_000005845.2_ASM584v2/GCF_000005845.2_ASM584v2_genomic.fna.gz
wget -O NC_000913.3.fasta 'https://www.ncbi.nlm.nih.gov/search/api/sequence/NC_000913.3/?report=fasta'
Synthesis project: www.sciencemag.org/news/2016/08/biologists-are-close-reinventing-genetic-code-life
Omics modeling: www.ncbi.nlm.nih.gov/pmc/articles/PMC5611438/ Tools for Genomic and Transcriptomic Analysis of Microbes at Single-Cell Level Zixi Chen, Lei Chen, Weiwen Zhang.
Creator of Primer
youtube.fandom.com/wiki/Primer gives real identity:Feels exactly the background you'd expect: disilusioned by the educational system, and working to make education better! Great guy! Reminds Ciro Santilli of himself a bit.
- the name is Justin Helps from Minnesota
- dropped out of his PhD that got boring, and used to work at Khan Academy
- LinkedIn gives PhD subject: www.linkedin.com/in/justin-helps/ as materials science
- twitter.com/helpsypoo personal Twitter account
Face reveal at: www.youtube.com/watch?v=QC91Bf8hQVo
How to blackout your window without drilling One year update Updated 2025-05-23 +Created 1970-01-01
One problem popped up about one year after having bought the blinds in 2019: the blind won't stay still except at the most closed position. Anywhere above it started to slowly go up by itself.
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