Microscopy connectome extraction Updated +Created
This is the most plausible way of obtaining a full connectome looking from 2020 forward. Then you'd observe the slices with an electron microscope + appropriate Staining. Superintelligence by Nick Bostrom (2014) really opened Ciro Santilli's eyes to this possibility.
Once this is done for a human, it will be one of the greatest milestone of humanities, coparable perhaps to the Human Genome Project. BUt of course, privacy issues are incrediby pressing in this case, even more than in the human genome project, as we would essentially be able to read the brain of the person after their death.
As of 2022, the Drosophila connectome had been almost fully extracted.
This is also a possible path towards post-mortem brain reading.
Figure 1. Source. Unconfirmed, but looks like the type of frozen brain where a Microtome would be used.
Mind uploading Updated +Created
Wikipedia defines Mind uploading as a synonym for whole brain emulation. This sounds really weird, as "mind uploading" suggests much more simply brain dumping, or perhaps reuploading a brain dump to a brain.
Superintelligence by Nick Bostrom (2014) section "Whole brain emulation" provides a reasonable setup: post mortem, take a brain, freeze it, then cut it into fine slices with a Microtome, and then inspect slices with an electron microscope after some kind of staining to determine all the synapses.
Likely implies AGI.
SlidableWorm Updated +Created
Fantastic resouce that contains cross sections of C. elegans at various lengths of its body. Presumably frozen and cut with a Microtome and then scanned with electron microscopy.
Shame that there are so many parts missing.
Visible Human Project Updated +Created
Frozen and cut on Microtome at 1mm intervals.