Follows the "certified teacher only" approach which is in Ciro Santilli's opinion a fatal flaw of most elearning systems out there, OurBigBook.com won't suffer from that!
All notes appear to have been extracted from existing notes, as noted on the bottom of each page.
Appears to have mixed licenses. E.g.:
- phys.libretexts.org/Bookshelves/University_Physics/Book%3A_University_Physics_(OpenStax)/Book%3A_University_Physics_III_-_Optics_and_Modern_Physics_(OpenStax)/06%3A_Photons_and_Matter_Waves/6.06%3A_De_Broglies_Matter_Waves is CC BY
- but we had seen another one that was CC BY-NC-SA
- phys.libretexts.org/Courses/University_of_California_Davis/UCD%3A_Physics_9HE_-_Modern_Physics/06%3A_Emission_and_Absorption_of_Photons/6.1%3A_Transitions_Between_Stationary_States CC BY-SA
- chem.libretexts.org/Bookshelves/Introductory_Chemistry/Introductory_Chemistry_(CK-12) uses the custom "CK-12 license" which seems a bit like CC BY-NC-SA
- some don't even have a free license, e.g.: phys.libretexts.org/Bookshelves/Quantum_Mechanics/Quantum_Mechanics_(Fowler)/00%3A_Front_Matter/04%3A_Licensing
TODO how does it work exactly? Do they ask for permission from authors in every case, including when the content has open license? Or when it has open license, do they just do it? In some cases, the notes have no license, so they must have asked.
TODO what is the source code that authors write? LaTeX or something else? LaTeX feels extremely likely given that it is what most original materials were already written in.
They are attempting a "model up this entire university" thing: phys.libretexts.org/Courses which is good. E.g. they have a bunch of "quantum mechanics ones under: phys.libretexts.org/Bookshelves/Quantum_Mechanics
Appears to be UC Davies-based mostly.
They claim to use this closed source backend: www.nice.com/resources/cxone-expert-knowledge-management? Seriously? For a publicly funded project with low-tech requirements?? It is mind blowing.
Some issues:
- the internal cross references are somewhat broken as of 2022.
- their URLs are HUGE! All components of every ancestor are in it. E.g. check this out: phys.libretexts.org/Bookshelves/Quantum_Mechanics/Introductory_Quantum_Mechanics_(Fitzpatrick)/12%3A_Time-Dependent_Perturbation_Theory/12.13%3A_Forbidden_Transitions Insane.
This is an interesting initiative which has some similarities to Ciro Santilli's OurBigBook project.
The fatal flaw of the initiative in Ciro Santilli's opinion is the lack of user-generated content. We will never get there without UGC and algorithms, never.
Also as of 2021, it mostly useless business courses: learn.saylor.org unfortunately.
But it has several redeeming factors which Ciro Santilli aproves of:
- exam as a service-like
- they have a GitHub: github.com/saylordotorgo
The founder Michael J. Saylor looks a bit crooked, Rich people who create charitable prizes are often crooked comes to mind. But maybe he's just weird.
Michael Saylor interview by Lex Fridman (2022)
Source. At the timestamp:What statement... maybe he's actually not crooked, maybe it was just an accounting mistake... God, why.
When I go, all my assets will flow into a foundation, and the foundation's mission is to make education free for everybody forever.
If only Ciro Santilli knew how to contact him and convince him that his current approach is innefective and that Ciro has something better! Michael, please Google into this page some day, Ciro Santilli needs funding for OurBigBook.com. A hopeless Tweet at: twitter.com/cirosantilli/status/1548350114623660035. Also tried to hit his
[email protected].No mention of education specifically on website. But at www.washingtonpost.com/wp-srv/liveonline/00/business/saylor0621.htm from Michael J. Saylor they did show interest, so adding to this Educational charitable organization list anyways.
Of all the rich person foundations, this is the one that feels the most hardcore.
They put huge focus on autism. Do they have an autistic child? Yes: www.forbes.com/pictures/eilm45mll/james-simons-autism/?sh=7825234250ce his daughter.
Although this was one of the children cartoons Ciro Santilli liked to watch, watching Dragon Ball Z as an adult feels like watching paint dry, everything takes forever! Apparently padding to sync with the manga: www.quora.com/Why-does-DBZ-drag-on-for-so-long The original Dragon Ball was likely strictly better, as it was much more fun and took itself less seriously. Also in DBZ power level inflation is taken to ridiculous levels. This is why One-Punch Man is good. Out of all evil characters, Frieza is one that made a big impression on Ciro, his graphical design is so good.
This experiment seems to be really hard to do, and so there aren't many super clear demonstration videos with full experimental setup description out there unfortunately.
For single-photon non-double-slit experiments see: single photon production and detection experiments. Those are basically a pre-requisite to this.
photon experiments:
- aapt.scitation.org/doi/full/10.1119/1.4955173 "Video recording true single-photon double-slit interference" by Aspden and Padgetta (2016). Abstract says using spontaneous parametric down-conversion detection of the second photon to know when to turn the camera on
Non-elementary particle:
- 2019-10-08: 25,000 Daltons
- interactive.quantumnano.at/letsgo/ awesome interactive demo that allows you to control many parameters on a lab. Written in Flash unfortunately, in 2015... what a lack of future proofing!
Are particles bounced by the first wall in the double slit experiment? by 
Ciro Santilli 40 Updated 2025-07-16
Ciro Santilli 40 Updated 2025-07-16It would be amazing to answer this with single particle double slit experiment measurements!
Ciro Santilli believes that the Donald Trump bans were extremely unfair, and highlight the need for government to ensure greater freedom of speech in social media, more information at: cirosantilli.com/china-dictatorship/unjust-social-media-censorship-in-the-west, related: globalization reduces the power of governments.
Can be seen as a cheap form of DNA sequencing that only test for a few hits. Some major applications:
- gene expression profiling
- single-nucleotide polymorphism: specificity is high enough to detect snips
Experiments that involve sequencing bulk DNA found in a sample to determine what species are present, as opposed to sequencing just a single specific specimen. Examples of samples that are often used:
- river water to determine which bacteria are present, notably to determine if the water is free of dangerous bacteria. A concrete example is shown at: Section "How to use an Oxford Nanopore MinION to extract DNA from river water and determine which bacteria live in it".
- sea water biodiversity: ocean-microbiome.embl.de/companion.html
- food, including searching for desirable microorganisms such as in cheese or bread yeast
- poo, e.g. to study how the human microbiome influences health. There are companies actively working on this, e.g.: www.microbiotica.com/
One related application which most people would not consider metagenomics, is that of finding circulating tumor DNA in blood to detect tumors.
- techcrunch.com/2022/05/31/ultima-genomics-claims-100-full-genome-sequencing-after-stealth-600m-raise/ Ultima genomics TODO technology? Promises 100 USD genome, 600M funding out of stealth...
oriC = Origin of Chromosomal replication.
Caused by slipped strand mispairing.
This is an extremely widely used technique as of 2020 and much earlier.
If allows you to amplify "any" sequence of choice (TODO length limitations) between a start and end sequences of interest which you synthesize.
If the sequence of interest is present, it gets amplified exponentially, and you end up with a bunch of DNA at the end.
You can then measure the DNA concentration based on simple light refraction methods to see if there is a lot of DNA or not in the post-processed sample.
Even Ciro Santilli had some contact with it at: Section "How to use an Oxford Nanopore MinION to extract DNA from river water and determine which bacteria live in it", see: PCR!
One common problem that happens with PCR if you don't design your primers right is: en.wikipedia.org/wiki/Primer_dimer
Sometime it fails: www.reddit.com/r/molecularbiology/comments/1kouomw/when_your_pcr_fails_again_and_you_start/and a comment:
Nothing humbles you faster than a bandless gel. One minute you’re a scientist, the next you’re just a pipette-wielding wizard casting spells that don’t work. Meanwhile, physicists are out there acting like gravity always behaves. Smash that upvote if your reagents have ever gaslit you.
PCR = Pray, Cry, Repeat
There are unlisted articles, also show them or only show them.