The debiased Lasso adds an approximate inverse-Gram correction to a Lasso estimate so that each corrected coordinate has an asymptotically linear expansion.
Let and use Nodewise Lasso with and nonzero design columns. Form with entry equal to one and other entries , and put row of equal to . The nodewise-Lasso residual identity and the Karush-Kuhn-Tucker conditions show that the diagonal of equals one and its row- off-diagonal entries have magnitude at most . For the Debiased Lasso,
The displayed bound follows row by row from Holder inequality. If the noise is conditionally multivariate normal with covariance , and the nodewise fits and tuning parameters depend only on , the first term is conditionally normal with covariance .
A matrix is an -approximate inverse of a Gram matrix in entrywise maximum norm when
This turns the bias remainder of a Debiased Lasso into a product of and the coefficient error.
The nodewise Lasso regresses each design column on the remaining columns and uses its residual to estimate a column of the inverse covariance or inverse Gram matrix.
For Nodewise Lasso with objective , put . Its Karush-Kuhn-Tucker conditions give with . Hence
For this is positive whenever ; if it were zero both nonnegative terms would vanish, forcing and . Nonzero columns are therefore an essential hypothesis for division by this quantity.
Under sparsity, compatibility, and inverse-Gram estimation conditions, the standardized coordinatewise error of the Debiased Lasso converges in distribution to a standard normal distribution.
In the normal linear model, assume is independent of . Independent rows of with multivariate normal distribution give a simple random design for Debiased Lasso. Let , and , with fixed positive noise scale. Choose the Lasso penalty and all Nodewise Lasso penalties as sufficiently large constant multiples of , including the noise scale in the former. Uniform sample cross-correlations are bounded by this scale, so zero is the nodewise solution with probability tending to one. Column squared norms divided by converge uniformly to one. To check the Compatibility condition for the Lasso directly, put and . On the Lasso cone condition, , and the Cauchy-Schwarz inequality gives
For , entrywise concentration of a Gaussian Gram matrix gives with probability tending to one for sufficiently large fixed . The stated sparsity condition implies on this event, so one can take eventually. The conditional Gaussian tail bound for the noise score and the Basic inequality for the Lasso then give with probability tending to one. Consequently the debiased-Lasso remainder bound is at most with probability tending to one, for a fixed constant . These assumptions allow both and to grow, for example , .

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