Florian C. Oberstrass investigated the structure of the polypyrimidine tract-binding protein bound to RNA. The work connected sequence recognition with the arrangement of RNA-binding domains and the regulation of RNA splicing.[ref]
Structure of PTB bound to RNA: specific binding and implications for splicing regulation by Florian C. Oberstrass and others. 2005, abstract: PTB–RNA structure and implications for splicing regulation
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