A Gα family member that can stimulate adenylyl cyclase.
Receptor-promoted nucleotide exchange helps activate the switch, and GTP hydrolysis contributes to termination. Increased cyclic AMP then regulates effectors such as protein kinase A, turning a cell-surface recognition event into intracellular phosphorylation. [ref]
Molecular Biology of the Cell, 4th edition by Bruce Alberts and others. Chapters 3, 6 and 15, protein function, translation and cell signalling
Articles by others on the same topic
There are currently no matching articles.