A heterotrimeric G protein is a signaling assembly with , and subunits. Receptor-promoted nucleotide exchange on regulates interactions with and effectors; both signaling components can contribute downstream.
The associated β and γ subunits of a heterotrimeric G protein. Their interactions with downstream effectors transmit signals as well as support heterotrimer assembly.
The guanine-nucleotide-binding subunit of a heterotrimeric G protein. Nucleotide state changes its interactions with receptors, Gβγ and effectors.
A Gα family member that can inhibit adenylyl cyclase.
A Gα family member that can stimulate adenylyl cyclase.
A Gα family member that activates phospholipase C signalling.
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