A class of proteins that package DNA within chromatin. Specific modifications and binding partners help determine local regulatory behavior.
A distinct histone sequence with properties or localization differing from another histone of the same broad class. CENP-A provides a specialized centromeric example.
The centromere-associated histone-H3 variant supporting kinetochore assembly. Its genomic occupancy helps mark centromeric identity, which can persist without one universal underlying repeat sequence.
A histone associated with nucleosomal linker regions and higher-order organization, distinct from a member of the core histone octamer.
A core histone carrying several sites of regulatory modification, including the lysine modified in H3K9 methylation.

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Histone by Ciro Santilli 40 Updated 2025-07-16
These are apparenty an important part of transcriptional regulation given the number of modifications they can undergo! Quite exciting.