Addition of acetyl groups to histones. Its functional effects depend on the site, associated readers and local chromatin context.
Removal of acetyl groups can alter histone interactions and recruitment of chromatin-associated factors. Its association with silencing should be interpreted at the specified loci and developmental stage rather than as a universal consequence of every histone deacetylation event. [ref]
Molecular Biology of the Cell, 4th edition by Bruce Alberts and others. Chapters 4–7, chromatin, replication and gene regulation
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