A standard one-sided version is as follows. Let be differentiable on , with there. Suppose either as , or there. If
then . The denominator is nonzero sufficiently near the endpoint. Corresponding versions apply at other finite endpoints and at infinity. The quotient of derivatives must have a limit; differentiating numerator and denominator is not an unrestricted quotient identity.
In the zero-over-zero case, extend both functions continuously to the endpoint by zero and use the Cauchy mean value theorem to write for an intermediate . For example, as . The rule is sufficient, not necessary: as , while its derivative ratio has no limit. Without the required indeterminate setting, it can give a wrong answer: diverges at zero although its derivative ratio is one.
The usual zero-over-zero L'Hopital rule requires the denominator's derivative to be nonzero throughout a sufficiently small deleted neighborhood. A limit taken only where that derivative is nonzero is insufficient. An explicit counterexample uses , , and . On put and . On put and . Extend beyond one. Values and first derivatives agree at the joins, both functions tend to zero, and is positive. Where , it lies inside a transition interval and . Thus has natural-domain limit zero, but equals zero at and one at , so has no limit.

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