A checkpoint component participating in inhibition of Cdc20 as part of the mitotic checkpoint complex.
Changes in its interactions support assembly of a signal that restrains anaphase-promoting activity when chromosome attachment is inadequate. This converts an unsatisfied local attachment state into a delay of the global chromosome-separation decision. [ref]
Molecular Biology of the Cell, 4th edition by Bruce Alberts and others. Chapter 17, The Spindle Assembly Checkpoint
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