The mean-vector prediction risk measures squared Euclidean norm error in estimating the deterministic response mean. For independent future noise with covariance matrix , prediction of a new noisy response adds to this risk. A Gaussian orthogonal projection matrix of rank has risk .
For and a fixed orthogonal projection matrix of rank , the displayed expression is an unbiased estimator of the mean-vector prediction risk whenever is an unbiased estimator of . Independence of its two terms is unnecessary. Comparing fixed models yields the Mallows Cp penalty, but minimizing unbiased estimates does not preserve unbiasedness after selection.
For a normal distribution with unrestricted and unknown , an integrable data-only unbiased estimator of the mean-vector prediction risk of a fixed rank- orthogonal projection matrix exists exactly when . To prove necessity, randomize the mean by independent Gaussian variance : conditioning adds to the squared bias term, whereas the marginal variance identity would add . When , the residual sum of squares itself is unbiased.

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