Notch signalling is a contact-dependent signalling pathway in which a ligand on one cell activates a receptor on another. Proteolytic processing releases an intracellular receptor fragment that can enter the cell nucleus and participate in transcription control. receptor processing therefore links a local contact to a nuclear response. During vertebrate somitogenesis, coupling through Notch signalling can coordinate neighbouring oscillators without being identical to their intracellular oscillation mechanism. [ref]

Ancestors (3)

  1. Signal transduction
  2. Biology
  3. Home

Incoming links (3)

View article source

Discussion (0) New discussion

There are no discussions about this article yet.

Articles by others on the same topic (0)

There are currently no matching articles.
See all articles in the same topic Create my own version