For a Cox proportional-hazards model, let denote the logarithm of the Cox partial likelihood. To compare a full parameter space with a nested null model imposing independent smooth restrictions, maximize the same partial likelihood under each model and formNesting makes . Under the null hypothesis, a correctly specified regular model, independent censoring conditional on covariates, fixed parameter dimension, an interior true parameter and nonsingular limiting information, . The degrees of freedom count independent restrictions, not the number of observed failures. For example, testing that two identifiable regression coefficients both vanish gives .
The calibration follows from the local quadratic expansion of : the unrestricted maximizer removes the score component in the constrained directions, whose standardized squared length has a chi-squared distribution. It requires enough event information for this approximation. A variance parameter constrained to be nonnegative and tested at zero, or a parameter unidentified under the null model, violates the regular interior assumptions; an ordinary reference cannot be presumed. Model comparisons must also use the same observations and the same event-tie convention.
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