The marginal likelihood integrates the likelihood function against the prior density:
It is the normalizing constant in Bayes' theorem. For the subsequent posterior distribution and importance sampling calculations, assume a normalized prior density and .
Write . Choose an interior maximum a posteriori estimate, a globally maximizing posterior mode
Suppose is twice continuously differentiable near and its negative Hessian matrix is a positive-definite matrix. The second-order Taylor expansion is
Exponentiating and normalizing this local approximation gives the Laplace approximation
Thus the approximate mean is the posterior mode, and the approximate covariance matrix is the inverse local curvature. This normal approximation is useful when most posterior probability is concentrated around this mode. A boundary mode, singular curvature, or several substantial modes requires a modified approximation.
Evaluate Bayes' theorem at the posterior mode :
The multivariate normal density in the Laplace approximation has height at its mean. Therefore
Equivalently, the approximate log marginal likelihood is
The determinant factor accounts for the volume of the locally plausible parameter region, which the peak likelihood alone does not measure.

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