Take and use primes for spatial derivatives. Two integration by parts operations in the first variation of the elastic filament's bending energy give
Thus the Euler-Lagrange equation is , and the fluctuation differential operator is . In the L2 space inner product, its boundary form is
The conjugate endpoint trace pairs are and . Requiring one member of each pair to vanish gives the four standard self-adjoint endpoint conditions for filament bending, applied at both ends:
Each pair annihilates the boundary form for all in the domain. Conversely, the remaining two endpoint traces can be chosen freely: requiring the boundary form to vanish against every such forces an adjoint-domain function to satisfy the same two conditions. This proves self-adjointness, rather than just formal symmetry, on the corresponding fourth-order Sobolev space domain.
The count four concerns these elementary homogeneous choices. Identical-end boundary conditions do not restrict all self-adjoint operators to these four possibilities. For example, , at both ends, with any fixed real , also annihilates the boundary form: the remaining expression is . This Robin boundary condition supplies a continuous family beyond the four listed pairs.

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