Use the usual normal linear model , with fixed full-column-rank design , , and . These Gaussian distribution and constant-variance hypotheses are necessary for an exact finite-sample Student's t-test. Put and . The vector of ordinary least squares estimators satisfies
With , the test statistic is
Under the null hypothesis, has Student's t-distribution with degrees of freedom. A two-sided level- Student's t-test rejects when . If the intended test is one-sided against , it rejects when ; the statistical power conclusion below holds for either convention.

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