Write the linear mean model as
The errors are independent but heteroscedastic. Minimizing the unweighted residual sum of squares
gives the normal equation
Thus, provided ,
Since ,
Hence it is an unbiased estimator. This is the least-squares part of the estimators for a Poisson exposure model.
Ignoring terms independent of , the log-likelihood is
Its score function is
Since , the interior critical point is the maximum, giving
The sum of independent Poisson distributions is Poisson with mean , so
Thus the maximum-likelihood estimator is also unbiased.
Put
Independence and give
whereas gives
The Cauchy-Schwarz inequality, applied to and , yields
Consequently
Equality holds exactly when all positive exposures are equal. This is the variance comparison for Poisson exposure estimators.
Both alternatives have larger , so use upper-tail rejection regions. Let be the 95th quantile of the standard normal distribution.
For the likelihood estimator,
When is large, the normal approximation to the Poisson distribution gives, under ,
An approximate size- test therefore rejects when
When every is large, independently. A linear combination of independent normal variables is normal, so under ,
The corresponding approximate size- test rejects when
In both cases the null rejection probability is approximately , while values near the alternative mean increasingly fall in the rejection region as the total exposure grows. These are the normal-approximation tests for a Poisson exposure model.

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