Minimize . Differentiation gives the normal equations . Full column rank makes positive definite, so
The expectation uses the zero error mean; the covariance uses . With independent Gaussian errors of common variance, maximizing likelihood minimizes exactly the same residual sum of squares, so this is also the maximum likelihood estimator, whether the common variance is known or estimated.
For the quadratic design, decompose each group's residual sum of squares into its within-group constant plus the group size times the squared residual of its sample mean. The three parameter combinations , and can fit all three group means exactly. Therefore
The group means are independent normal variables, with variances . Hence their two stated linear combinations are jointly normal, and
Joint normality therefore proves the two estimators are independent. Their variances are and , respectively. Equal replication at the two off-center temperatures is what cancels the covariance.

Articles by others on the same topic (0)

There are currently no matching articles.