Measure an unwanted effect separately or design a comparison in which it cancels. Calibration against reference standards at several settings tests zero offset, gain and nonlinearity. Blanks reveal background. Reversal is useful when the wanted response is odd and the nuisance is even: gives and . For example reversing current in a resistance measurement cancels a stable thermoelectric voltage, but does not cancel the current-scale error or even-in-current Joule heating.
Interleave reversals to detect drift; interchange sensors or leads to expose asymmetry. Null or bridge methods reduce dependence on detector gain. Alignment checks, shielding and temperature control target specified physical couplings. Independent measurement methods provide a stronger test than repetition of the same setup. Repeated readings reduce independent random errors, not a shared bias. Correct significant identified effects and propagate the uncertainty of the correction and standards; complete removal of an unknown systematic error cannot generally be certified.[ref]
Guidelines for Evaluating and Expressing the Uncertainty of NIST Measurement Results by Barry N. Taylor and Chris E. Kuyatt. §5.2, uncertainty remaining after systematic-effect corrections
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