Spherical-particle wrapping by a fluid membrane ($E/(\pi \kappa )=(4-2\bar{w})\xi +\bar{\sigma }{\xi }^2$)

In a bound-cap model, an adhered sphere of radius $r$ covers area $A=2\pi r^2\xi$ with $\xi =1-\cos \alpha \in [0,2]$. Its excess area over its circular footprint is $\pi r^2{\xi }^2$. The Helfrich energy of that spherical cap is $4\pi \kappa \xi$, adhesion gives $-wA$, and membrane tension gives $\sigma \pi r^2{\xi }^2$. Setting $\bar{w}=w{r}^2/\kappa$ and $\bar{\sigma }=\sigma r^2/\kappa$ yields the displayed expression. Free-surface deformation, neck structure, Gaussian curvature and topology changes are omitted. Full wrapping alone does not prove scission.

For positive membrane tension, the bound-cap energy is convex in indentation. Its constrained minimum is the unconstrained value $(\bar{w}-2)/\bar{\sigma }$ clipped to $[0,2]$. No wrapping occurs at $\bar{w}\le 2$, partial wrapping at $2<\bar{w}<2+2\bar{\sigma }$, and full wrapping at $\bar{w}\ge 2+2\bar{\sigma }$. At zero tension the expression is linear, with all indentations degenerate at $\bar{w}=2$. These phase boundaries belong to the specified cap model and can move when free-membrane and neck energies are included.