In the 2016 observational context, appropriate choices are as follows.
For atomic species, use optical transit spectra of Na I near and K I near , with Hubble Space Telescope/STIS or ground-based high-resolution instruments on Very Large Telescope/Keck telescope-class telescopes. Neutral/ionized ultraviolet metal lines offer additional diagnostics with Hubble Space Telescope. Resolving a line's shape and distinguishing stellar contamination matters as much as locating its wavelength.
For molecules, use near/mid-IR spectroscopy: water bands near , and , CO near and , methane near , and near or . Hubble Space Telescope/WFC3 samples water around --; ground-based Very Large Telescope/CRIRES or Keck telescope/NIRSPEC spectra target accessible near-IR windows such as CO at . Warm Spitzer Space Telescope provides and photometry, while cryogenic Spitzer Space Telescope spectra/longer-wavelength data are archival by 2016. A broadband eclipse point alone does not uniquely identify a molecule.
For atmospheric escape, use ultraviolet transit spectroscopy of H I Ly at , and suitable C/O/metal lines, with Hubble Space Telescope/STIS or COS. Extended, velocity-shifted absorption beyond the optical planet suggests an escaping envelope, although stellar variability, geocoronal emission and interstellar absorption require treatment. Ground-based H at probes excited hydrogen and is a complementary rather than interchangeable measure of neutral-hydrogen escape.
Three complementary methods available in the setting of this 2017 paper are:
Transmission probes the limb, eclipses probe the dayside, and direct imaging isolates spatially resolved planetary light. Radial velocities alone measure orbital motion rather than atmospheric composition; high-resolution planetary Doppler spectroscopy can instead detect atmospheric spectral lines if planetary light is isolated statistically.