Science communicator Updated 2025-07-16
SmartNIC Updated 2025-07-16
A network interface controller that does more than just the base OSI model protocols, notably in a programmable way.
- www.nextplatform.com/2022/05/11/intel-unrolls-dpu-roadmap-with-a-two-year-cadence/
- www.trentonsystems.com/blog/what-is-a-smartnic
- blogs.nvidia.com/blog/2021/10/29/what-is-a-smartnic/ "Some are using FPGAs which promise flexibility"
- www.servethehome.com/intel-ipu-exotic-answer-to-industry-dpu/ "Intel IPU is an Exotic Answer to the Industry DPU"
- 2022 www.datacenterdynamics.com/en/news/amd-to-buy-smartnic-firm-pensando-for-19-billion/ "AMD to buy SmartNIC firm Pensando for $1.9 billion"
- www.theregister.com/2022/06/14/alibaba_dpu_cloud/ mentions that Alibaba Cloud created their own.
Hyperscalers Lead The Way To The Future With SmartNICs by The Next Platform (2019)
Source. - youtu.be/kwroXmFJJf0?t=599 financial industry is one of the users, notably high-frequency trading
Associated article: www.nextplatform.com/2019/10/31/hypercalers-lead-the-way-to-the-future-with-smartnics/ mentions that:
Google is widely believed to be working on its own design.
Visual math HTML book Updated 2025-07-16
When you see some tagged examples, you will immediately know what this means.
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Cyclotron Updated 2025-07-16
Predecessor to the synchrotron.
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Open access Updated 2025-07-16
Social media feed that forces you to see posts by non-followed Updated 2025-07-16
During the early 2020s, many of the idiotic social media platforms started adding a non optional "feature" of suggesting feed posts by people you don't follow:
It must have been some A/B testing overload that made that decision to try and make things more addictive for everyone. Or perhaps as a way to drive revenue with people paying to cheat the algorithm and boost their posts.
European Union we need you.
DEF CON Updated 2025-07-16
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Nuclear magnetic resonance Updated 2025-07-16
Ciro Santilli once visited the chemistry department of a world leading university, and the chemists there were obsessed with NMR. They had small benchtop NMR machines. They had larger machines. They had a room full of huge machines. They had them in corridors and on desk tops. Chemists really love that stuff. More precisely, these are used for NMR spectroscopy, which helps identify what a sample is made of.
Introduction to NMR by Allery Chemistry
. Source. - only works with an odd number of nucleons
- apply strong magnetic field, this separates the energy of up and down spins. Most spins align with field.
- send radio waves into sample to make nucleons go to upper energy level. We can see that the energy difference is small since we are talking about radio waves, low frequency.
- when nucleon goes back down, it re-emits radio waves, and we detect that. TODO: how do we not get that confused with the input wave, which is presumably at the same frequency? It appears to send pulses, and then wait for the response.
How to Prepare and Run a NMR Sample by University of Bath (2017)
Source. This is a more direct howto, cool to see. Uses a Bruker Corporation 300. They have a robotic arm add-on. Shows spectrum on computer screen at the end. Shame no molecule identification after that!This video has the merit of showing real equipment usage, including sample preparation.
Says clearly that NMR is the most important way to identify organic compounds.
- youtu.be/uNM801B9Y84?t=41 lists some of the most common targets, including hydrogen and carbon-13
- youtu.be/uNM801B9Y84?t=124 ethanol example
- youtu.be/uNM801B9Y84?t=251 they use solvents where all protium is replaced by deuterium to not affect results. Genius.
- youtu.be/uNM801B9Y84?t=354 usually they do 16 radio wave pulses
Introductory NMR & MRI: Video 01 by Magritek (2009)
Source. Precession and Resonance. Precession has a natural frequency for any angle of the wheel.Introductory NMR & MRI: Video 02 by Magritek (2009)
Source. The influence of temperature on spin statistics. At 300K, the number of up and down spins are very similar. As you reduce temperature, we get more and more on lower energy state.Introductory NMR & MRI: Video 03 by Magritek (2009)
Source. The influence of temperature on spin statistics. At 300K, the number of up and down spins are very similar. As you reduce temperature, we get more and more on lower energy state.NMR spectroscopy visualized by ScienceSketch
. Source. 2020. Decent explanation with animation. Could go into a bit more numbers, but OK. Nuclear triad Updated 2025-07-16
Open knowledge Updated 2025-07-16
The outcome of closed knowledge is reverse engineering.
Solexa Updated 2025-07-16
Instead of trying to dominate the sequencing market and gain trillions of dollars from it, they local British early stage investors were more than happy to get a 20x return on their small initial investments, and sold out to the Americans who will then make the real profit.
And now Solexa doesn't even have its own Wikipedia page, while Illumina is set out to be the next Microsoft. What a disgrace.
Cambridge visitors can still visit the Panton Arms pub, which was the location of the legendary "hey we should talk" founders meeting, chosen due to its proximity to the chemistry department of the University of Cambridge.
In 2021 the founders were awarded the Breakthrough Prize. The third person awarded was Pascal Mayer. He was apparently at Serono Pharmaceutical Research Institute at the time of development. They do have a wiki page unlike Solexa: en.wikipedia.org/wiki/Serono. They paid a 700 million fine in 2005 in the United States, and sold out in 2006 to Merck for 10 billion USD.
Bibliography:
- medium.com/@nick.mccooke/how-we-pioneered-next-generation-dna-sequencing-at-solexa-61bac41aedd2 How We Pioneered Next Generation DNA Sequencing At Solexal by Nick McCooke 2025. This article series could be very interesting.
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