Power, Sex, Suicide by Nick Lane (2006) by 
Ciro Santilli 35 Updated 2025-04-24 +Created 1970-01-01
Ciro Santilli 35 Updated 2025-04-24 +Created 1970-01-01All pages below are from the second edition from 2018. It seems that there weren't any changes in the text, the updated preface mentions
As it happens, nearly 15 years have passed since the 1st edition of Power, Sex, Suicide was published, and I am resisting the temptation to make any lame revisions. Some say that even Darwin lessened the power of his arguments in the Origin of Species through his multiple revisions, in which he dealt with criticisms and sometimes shifted his views in the wrong direction. I prefer my original to speak for itself, even if it turns out to be wrong.
This is partly addressed in the preface of the second edition from 2018.
Central thesis:
- there are two sexes because of mitochondria
- the acquisition of mitochondria was one of the most important steps in the evolution of eukaryotes.There are no known eukaryotes which never had mitochondria. Having mitochondria appears to be a requisite for being an eukaryote.Contrast this for example with multicellularity, which is highly polyphyletic.
- Apoptosis is largely regulated by mitochondria
- there are two main theories for how the mitochondria endosymbiosis started:
- parsitic hypothesis of mitochondrial endosymbiosis: a parasitic option rather than cooperative
- hydrogen hypothesis: a cooperative option rather than parasitic
Smaller points:
- 10% of our body weight (dry presumably?) is mitochondria. Also quoted at: www.nature.com/scitable/blog/student-voices/mighty_mitochondria. TODO confirm.
- eukaryotes can do phatocytosis due to their cytoskeleton
- paints a colorful picture of Peter Mitchell. Some Wikipedia edits are warranted!
- it is hard for complex organisms to evolve because longer DNA means longer replication time
- cancer is natural selection gone wrong
- multicellular organisms are not utopias where every cell lives happily. Rather, they are dictatorships, where any dissident is forced to commit seppuku. Lu Xun's petition quote comes to mind.
Nitpicks:
- the book calls ATP synthase "ATPase" in several points, which is confusing because -ase means "something that breaks", and in 2020 parlance, there are ATPases which actually break ATP: en.wikipedia.org/wiki/ATPase. The book itself acknowledges that on page 135:
The ATPase is freely reversible. Under some circumstances it can go into reverse, whereupon it splits ATP, and uses the energy released to pump protons up the drive shaft, back across the membrane against the pressure of the reservoir. In fact the very name ATPase (rather than ATP synthase) signifies this action, which was discovered first. This bizarre trait hides a deep secret of life, and we’ll return to it in a moment.
Some criticisms:
- some of the later chapters are a bit more boring, like the stuff about warm-blooded animals. Perhaps is it that Ciro Santilli is more interested in the molecular aspects than macro
- the author talks about some very recent research at the time. While this does highlight his expertise, some of the points mentioned might still be in a state of flow. This is acknowledged by the author himself on the 2018 updated preface however.
Biologists are obsessed with these!
When plugged into Ubuntu 22.04 via the USB Micro-B the Micro Bit mounts as:e.g.:for username
/media/$USER/MICROBIT//media/ciro/MICROBIT/ciro.Loading the program is done by simply copying a The file name does not matter, only the
.hex binary into the image e.g. with:cp ~/Downloads/microbit_program.hex /media/$USER/MICROBIT/.hex extension.Identification: kitronik.co.uk/blogs/resources/explore-micro-bit-v1-microbit-v2-differences The easiest thing is perhaps the GPIO notches.
Second quantization also appears to be useful not only for relativistic quantum mechanics, but also for condensed matter physics. The reason is that the basis idea is to use the number occupation basis. This basis is:
- convenient for quantum field theory because of particle creation and annihilation changes the number of particles all the time
- convenient for condensed matter physics because there you have a gazillion particles occupying entire energy bands
Bibliography:
- www.youtube.com/watch?v=MVqOfEYzwFY "How to Visualize Quantum Field Theory" by ZAP Physics (2020). Has 1D simulations on a circle. Starts towards the right direction, but is a bit lacking unfortunately, could go deeper.
The exact same problem appears over and over, e.g.:
- transportaion: the last mile of the trip when everyone leaves the train and goes to their different respective offices is the most expensive
- telecommunications: the last mile of wire linking local hubs to actual homes is the most expensive
- electrical grid: same as telecommunications
Ciro Santilli also identified knowledge version of this problem: the missing link between basic and advanced.
Creator of QEMU and FFmpeg, both of which Ciro Santilli deeply respects. And a bunch other random stuff.
What is shocking about Fabrice this is that both are insanely important software that Ciro Santilli really likes, and both seem to be completely unrelated subjects!
Google made billions on top of this dude:
- FFmpeg is the backend of YouTube
- QEMU is the default emulator for Android Studio as of 2019, which Android developers use by default under the hood to develop Android Apps on their desktop without the need for a real device.
At last but not least, Fabrice also studied in the same school that Ciro Santilli studied in France, École Polytechnique.
It is a shame that he keeps such a low profile, there are no videos of him on the web, and he declines interviews.
Another surprising fact is that Fabrice has not worked for the "Big Tech Companies" as far as can be publicly seen, but rather mostly on smaller companies that he co-founded: www.quora.com/Computer-Programmers/Computer-Programmers-Where-is-Fabrice-Bellard-employed
And he's also into some completely random projcts unsurprisingly:
- www.computerhistory.org/tdih/january/6/ Computer Scientist Fabrice Bellard Announces Computing Pi to Record Number of Digits
Bibliography:
- smartbear.com/de/blog/2011/fabrice-bellard-portrait-of-a-super-productive-pro/ contains a list of his projects as of 2011
Fabrice Bellard in 2007
. Source. At a restaurant with the author apparently. Plus Miguel De Icaza who was in Paris for some conference, which they all presumably attended.
Fabrice Bellard with light
. There are no in-focus images of Fabrice on the Internet.This dude is interesting. Quite crazy type. It is hard to differentiate genius from mad.
Ciro Santilli bumps on his Stack Overflow from time to time: stackoverflow.com/users/1269037/dan-dascalescu.
You gotta be born after the year 2000 to understand it.
This is becoming more and more popular as a group chat with channels and threads possibility as of 2020.
Very similar to Slack.
They force your username to have 4 random digits? www.reddit.com/r/discordapp/comments/43kjdl/whats_the_number_next_to_the_username/
Not possible to anonymously join just one server without creating a new account? What's the point of servers then! www.reddit.com/r/discordapp/comments/6gmjl7/changing_nick_before_joining_a_new_server/ Oh, also nicks don't hide your username from the server in any way, you can get the original username by just clicking on the person's username.
No proper threaded discussion without creating new channels? As of 2022 there is kind of a way, but it was a bit obtuse.
As of 2022 they also have a school hub: support.discord.com/hc/en-us/articles/4406046651927-Discord-Student-Hubs-FAQ which auto creates groups by university email access. Good idea, and shows popularity amongst that user group.
Servers don't have an ID to join them? www.reddit.com/r/discordapp/comments/b9zdt6/join_discord_server_from_id/
Can only make public servers if you have 1000 members?? support.discord.com/hc/en-us/articles/360023968311 Why so much bullshit?? www.reddit.com/r/discordapp/comments/6jouf8/how_do_i_make_my_server_public/
Located in Cambridge, United Kingdom.
Second largest number of Nobel Prize as of 2019, need on say more? en.wikipedia.org/w/index.php?title=List_of_Nobel_laureates_by_university_affiliation&oldid=934987075
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