Topics (384k) Articles (398k) Users (410) Discussions (242) Comments (383) Files (13k) New article
A syndrome associated with toxin-producing Group A streptococcal infection, classically combining pharyngitis with a characteristic rash. The rash reflects a toxin-associated response rather than fungal invasion of skin.[ref]
Clinical Guidance for Scarlet Fever by CDC. Cause and features
Inflammation of the stomach and intestines, commonly associated with diarrhea and vomiting. The syndrome can arise from different infectious and noninfectious causes, so its name does not identify one pathogen.
Life-threatening organ dysfunction caused by a dysregulated response to infection. Infection, bloodstream organisms and sepsis are related but different findings; sepsis need not be defined by a positive blood culture.[ref]
Suspected sepsis in people aged 16 or over by NICE. Definition and recognition
A group of rickettsial infections, including epidemic typhus associated with body lice. The name is distinct from typhoid fever, which has a different organism and transmission route.[ref]
Clinical Overview of Epidemic Typhus by CDC. Cause and transmission
A toxin-mediated disease caused by Clostridium tetani. Tetanospasmin disrupts inhibitory neural signaling, producing rigidity and spasms; the wound is the microbial source rather than the site of every symptom.[ref]
Clinical Care of Tetanus by CDC. Disease mechanism
Microbial infection of an anatomical joint. Inflammation can damage articular structures, distinguishing it from noninfectious crystal-associated or autoimmune arthritis.
Inflammation of lymph nodes. Enlargement and tenderness can reflect a response to a nearby process, while the anatomical finding alone does not identify its infectious or noninfectious cause.
Inflammation or infection of the middle-ear space. Fluid behind the eardrum can affect sound conduction, connecting a local inflammatory process with temporary hearing loss.
A disease caused by poliovirus; paralytic disease is one possible consequence, not the result of every infection.
Inflammation of the membranes surrounding the brain and spinal cord. Its location differs from encephalitis, though both can occur together.
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.
Figure 3. Visual Studio Code extension installation.
Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. 
- Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact