JAMA Cardiology 2(10), 1090–1099 (2017); DOI 10.1001/jamacardio.2017.2945. Abstract, Importance and Exposures: comparison of thermodilution with estimated-oxygen-uptake Fick output. Full-text identifier: PMCID PMC5710449.
Primary Abstract, Design and Exposures, pubmed.ncbi.nlm.nih.gov/28877293/ : 12,232 Veterans Affairs participants and 3,391 Vanderbilt participants, paired thermodilution and estimated-oxygen-uptake Fick measurements during cardiac catheterization. Analyses used cardiac index normalized to body surface area. Results and Figure 1 distinguish a small mean difference from wide individual limits of agreement.
Manufacturer parameter definition, sections “What is O2Hb?” and “FO2Hb versus oxygen saturation (sO2)”: fractional oxyhemoglobin uses total hemoglobin, whereas functional saturation excludes carboxyhemoglobin and methemoglobin from its denominator.
Primary byline W. G. Zijlstra, A. Buursma and W. P. Meeuwsen-van der Roest. Clinical Chemistry 37(9), 1633–1638 (1991), DOI doi.org/10.1093/clinchem/37.9.1633 . Abstract: measured millimolar absorptivities for four fetal/adult human hemoglobin derivatives over 450–1000 nm; small fetal/adult spectral differences matter to multicomponent analysis. No full-name expansion inferred from initials.
Manufacturer technical parameter description, Hemoglobin: Structure and function and total-hemoglobin definition. Gives the worked oxygen-binding coefficient 1.34 mL oxygen per gram hemoglobin, distinguishes bound from dissolved oxygen and identifies carboxyhemoglobin/methemoglobin in total hemoglobin.
Additional manufacturer parameter definitions: www.radiometer.com/en/products/blood-gas-testing/parameters/methemoglobin , What is MetHb?, distinguishes ferric from ferrous haem; www.radiometer.com/en/products/blood-gas-testing/parameters/carboxyhemoglobin , What is COHb?, defines carbon-monoxide binding; www.radiometer.com/en/products/blood-gas-testing/parameters/oxygen-saturation , definition and Physiological background, defines functional saturation with oxyhemoglobin plus deoxyhemoglobin as denominator and states four oxygen molecules per fully occupied tetramer. These biochemical and measurement definitions are the cited locators; no clinical thresholds or management instructions are imported.
Primary byline S. Yaemsiri, N. Hou, M. M. Slining and K. He. Journal of the European Academy of Dermatology and Venereology 24(4), 420–423, April 2010; first online 8 September 2009. DOI 10.1111/j.1468-3083.2009.03426.x. The abstract describes 22 healthy young adults marking nails with a supplied file and measuring mark displacement over one to three months. Mean fingernail and toenail growth rates were 3.47 and 1.62 millimetres per month.
Wilbert Aarnoudse and colleagues, Journal of the American College of Cardiology 50(24), 2294–2304 (2007), DOI doi.org/10.1016/j.jacc.2007.08.047 . Primary byline and abstract, Methods: continuous saline infusion with an infusion catheter and pressure/temperature-sensing guidewire; validation in five dogs and 35 patients. The method estimates volumetric flow, not blood oxygen content.
Additional precise locators from the primary indexed abstract: Methods specifies a 2.8-F infusion catheter and a 0.014-inch pressure/temperature-sensing guidewire. Results gives the canine comparison regression , with .
C. E. Nerantzis and colleagues, Clinical Anatomy 9(1), 10–13 (1996), PMID 8838273. Primary byline and abstract: 200 human hearts studied after radiopaque injection by direct observation and X-ray analysis; 178 classified as right dominant by posterior interventricular arterial origin, with additional variation within that group.
Acta Biomaterialia72,342–351(2018); DOI10.1016/j.actbio.2018.02.016. Primary abstract and publisher www.sciencedirect.com/science/article/pii/S1742706118300862 . Complementary X-ray scattering, cross-polarized light microscopy and scanning electron microscopy; graded mineralized-collagen orientations and proposed connection with optical pattern. Initial-only first-author byline M.Albéric retained.
First-party NHS clinical explanation. Locator: What are the risks associated with a Split-Thickness Skin Graft (SSG)? Describes dependence on a healthy wound bed and ingrowth of new blood vessels for graft take. Used for physiological explanation only, not patient-specific advice or operative instructions.
US National Cancer Institute originating terminology entry. Locator: definition of skin graft as skin moved from one part of the body to another. Supports the basic tissue-transfer definition; not a source for a comparison of graft techniques.
Firsthand1999 interview of Jacques Miller by Frank Fenner, Australian Academy of Science. Sections Why did the mice waste away? An unexpected finding and So why did the mice waste away?: neonatal thymectomy, lymphocyte deficiency, graft acceptance/rescue, and germ-free comparison. Primary page explicitly verifies interviewee identity; no expansion inferred from an initial-only byline.
Official NCI definition: lymphatic organ behind the breastbone in which T lymphocytes grow and multiply. Entry checked3November2026.
European Journal of Pharmacology 41, 409–416 (1977), DOI 10.1016/0014-2999(77)90261-8. Abstract: isolated rabbit/rat thick ascending limbs, luminal drug application, reversible potential suppression and reduced chloride tracer efflux.
Human Reproduction10(1995),75–81. Primary publisher abstract/byline: R.Nahum,K.J.Thong,S.G.Hillier; four-day serum-free human thecal cultures, androstenedione assay, insulin/IGF treatments with/without LH. Steroid output changed without stimulated cell growth. Do not infer full names or clinical treatment conclusions.
Biology of Reproduction27(1982),703–711; DOI10.1095/biolreprod27.3.703. Original indexed title page/byline/abstract inspected; separated small/large cells from superovulated ewe corpora lutea on cycle days10–12. Large-cell unstimulated progesterone release approximately20fold that of equal small-cell counts. PubMed6291651. Initial-only bylines retained; direct PDF fetch failed, indexed original text readable.
Cell99(1999),649–659; DOI10.1016/S0092-8674(00)81553-6. Primary abstract: null mice, male sterility and freeze-fracture absence of tight-junction strands between Sertoli cells. Initial-only A.Gow retained. Slash in source title must be hyphenated in magic-link argument.
Journal of Steroid Biochemistry and Molecular Biology39(1991),19–25; DOI10.1016/0960-0760(91)90007-r. Initial-only first byline retained. Abstract: human luteinized granulosa-cell culture48h with/without hCG or FSH; progesterone/pregnenolone production and aromatase activity assayed separately. Used as a functional study of luteinized cells,not as proof of complete in-vivo luteinization from one hormone measurement.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 5. . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact