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The Dynamics of Glomerular Ultrafiltration in the Rat by Barry M. Brenner and others by
Codex 0 2026-11-05
Journal of Clinical Investigation50(1971),1776–1780; DOI10.1172/JCI106667. Publisher full byline verifies Barry M. Brenner,Julia L. Troy,Terrance M. Daugharty. Abstract: surface-glomerulus Wistar rats,servo-null capillary-pressure measurements,hydrostatic/oncotic-pressure estimates and single-nephron filtration. An October1971 correction is linked by the publisher; article text uses qualitative experimental conclusions and a separate explicitly hypothetical calculation,not the original numerical estimates.
Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle by T. M. Redmond and others by
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Primary laboratory description: RPE as a single cell layer at the back of the retina; RPE and photoreceptor cooperation in vitamin-A metabolism and vision.
Improved FSH sensitisation and aromatase assay in human granulosa-lutein cells by A. Lambert and others by
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Sertoli cells maintain Leydig cell number and peritubular myoid cell activity in the adult mouse testis by Diane Rebourcet and others by
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PLOS ONE9(2014),e105687; DOI10.1371/journal.pone.0105687. Original full byline verifies Diane Rebourcet. Transgenic selective Sertoli-cell ablation in adult mice; germ-cell loss, Leydig-cell decline and retained tubular architecture. Abstract and Results/Figures1,2,6. Animal-model results, not a proposed human treatment.
Nephrin is specifically located at the slit diaphragm of glomerular podocytes by V. Ruotsalainen and others by
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PNAS96(1999),7962–7967; DOI10.1073/pnas.96.14.7962. Abstract and immunolocalization: nephrin localized to the glomerular podocyte slit diaphragm. Initial-only first byline retained; full identity not guessed. Full text pmc.ncbi.nlm.nih.gov/articles/PMC22170/ .
Vitamin K Fact Sheet for Health Professionals by the Office of Dietary Supplements by
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NIH Office of Dietary Supplements, Introduction: fat-soluble compound family, K1/K2 forms and vitamin-K-dependent carboxylase. Used for biochemical definition only; no dose, personal treatment or medication-change recommendations.
Heparinase treatment suggests a role for the endothelial cell glycocalyx in regulation of capillary hematocrit by C. Desjardins and B. R. Duling by
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Preparation and study of fragments of single rabbit nephrons by M. Burg and others by
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Verified locator: American Journal of Physiology210(6),1293–1298,June1966; DOI10.1152/ajplegacy.1966.210.6.1293. Indexed byline M.Burg,J.Grantham,M.Abramow,J.Orloff retained without expansion. Original method-paper record verified; perfusion-method context also documented by the2022 Knepper remembrance. Do not confuse with the1997 reprint/commentary.
Intraluminal crawling of neutrophils to emigration sites: a molecularly distinct process from adhesion in the recruitment cascade by Mia Phillipson and others by
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By Mia Phillipson and others.
Verified locator: Journal of Experimental Medicine203(12),2569–2575(2006), DOI10.1084/jem.20060925. Byline verifies Mia Phillipson. Abstract/Results: intravital time-lapse microscopy in inflamed mouse postcapillary venules; crawling to exit sites distinct from initial adhesion. Figure1 specifies timed adhesion criteria. No clinical extrapolation.
Verified locator: Chapter1, sections1and5: dry-air/moist-air composition; humidity ratio Eq7, molecular-mass ratio0.621945 Eq8, specific humidity Eq9, distinctions from relative humidity. Definition and mass ratio are unit-independent; ideal-gas approximation used in worked derivation.
Dr. Andrew Schally, former Tulane endocrinologist and Nobel laureate, dies at 97 by Tulane University by
Codex 0 2026-11-05
Institutional history of the founding Metabolism Division chief. Describes growth-factor research, corticosteroid-binding globulin and research-center leadership.
A human calorimeter for the direct and indirect measurement of 24 h energy expenditure by M. J. Dauncey and others by
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British Journal of Nutrition 39(3),557–566 (1978); DOI10.1079/BJN19780071. Authors M. J. Dauncey, P. R. Murgatroyd and T. J. Cole. The indexed abstract describes a heat-sink direct calorimeter, open-circuit indirect measurements and evaporative heat loss inferred from inlet/outlet wet-and-dry-bulb temperatures and airflow.
Sodium chloride and water transport in the medullary thick ascending limb of Henle. Evidence for active chloride transport by Antonino S. Rocha and Juha P. Kokko by
Codex 0 2026-11-05
Journal of Clinical Investigation52(1973),612–623; DOI10.1172/JCI107223. Publisher verifies both full bylines. Abstract: isolated perfused rabbit medullary thick ascending limb; net fluid transport remained near zero under imposed osmotic gradients, while tubular NaCl concentration fell. The historical chloride-pump interpretation is not adopted as a complete modern molecular mechanism.
Sodium chloride and water transport in the descending limb of Henle by Juha P. Kokko by
Codex 0 2026-11-05
Journal of Clinical Investigation49(1970),1838–1846; DOI10.1172/JCI106401. Original publisher byline verifies Juha P. Kokko. Abstract: isolated perfused rabbit descending thin limbs, water efflux when bath osmolality raised with NaCl or raffinose, low sodium permeability. Restricted to tested segment and preparation.
Longitudinal section through Kidney by the Manipal Museum of Anatomy and Pathology by
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Vascular endothelial cells promote acute plasticity in ependymoglial cells of the neuroendocrine brain by Sandrine De Seranno and others by
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Journal of Neuroscience24(2004),10353–10363; DOI10.1523/JNEUROSCI.3228-04.2004. Abstract and Figure7: female-rat median-eminence explants incubated30min with/without500micromolar L-arginine; immunogold electron microscopy of GnRH terminals and pericapillary space. Culture experiments implicate endothelial nitric oxide in glial remodeling. Original indexed full text pmc.ncbi.nlm.nih.gov/articles/PMC6730291/ inspected; direct PMC CAPTCHA.
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.Figure 3. Visual Studio Code extension installation.Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. - Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact





