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A developmental biologist who investigated how FGF4 controls stable lineage restriction in the early mouse embryo, separating initial marker expression from later commitment.[ref]
A developmental biologist who studied self-organization of the epiblast, connecting extracellular context, rosette formation and lumenogenesis.[ref]
Self-organizing properties of mouse pluripotent cells initiate morphogenesis upon implantation by Ivan Bedzhov and Magdalena Zernicka-Goetz. Authorship and experimental findings
A developmental biologist who investigated how pluripotent cells organize during implantation, using embryo imaging and matrix-dependent cell culture.[ref]
Self-organizing properties of mouse pluripotent cells initiate morphogenesis upon implantation by Ivan Bedzhov and Magdalena Zernicka-Goetz. Authorship and experimental findings
A developmental biologist who studied Nodal signalling from the epiblast and its contribution to organization of the early mouse embryo.[ref]
Nodal signalling in the epiblast patterns the early mouse embryo by Jane Brennan and others. Authorship and experimental findings
A developmental biologist who investigated how graded Nodal signalling changes lineage contributions within the mouse organizer.[ref]
Cell fate decisions within the mouse organizer are governed by graded Nodal signals by Stéphane D. Vincent and others. Authorship and experimental findings
A developmental biologist who studied FGF signalling at the primitive streak, distinguishing cell fate specification from epithelial-to-mesenchymal transition.[ref]
FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak by Brian Ciruna and Janet Rossant. Authorship and experimental findings
A developmental biologist who investigated embryonic lineage specification, including how FGF signalling affects both mesoderm identity and morphogenetic movement.[ref]
FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak by Brian Ciruna and Janet Rossant. Authorship and experimental findings
A developmental biologist who studied the Bicoid gradient, testing how changes in its source and concentration shift positional outcomes in the Drosophila embryo.[ref]
The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner by Wolfgang Driever and Christiane Nüsslein-Volhard. Authorship and experimental findings
A developmental biologist who investigated genetic control of embryonic patterning, including how the Bicoid concentration gradient affects positional outcomes in Drosophila.[ref]
The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner by Wolfgang Driever and Christiane Nüsslein-Volhard. Authorship and experimental findings
A developmental biologist who tested how repression of maternal Hunchback contributes to Nanos-dependent posterior patterning in Drosophila.[ref]
The Drosophila posterior-group gene nanos functions by repressing hunchback activity by Vivian Irish and others. Authorship and experimental findings
A developmental biologist who investigated sequence-dependent control of translation by Nanos, connecting RNA regulatory elements to the posterior body pattern.[ref]
RNA regulatory elements mediate control of Drosophila body pattern by the posterior morphogen nanos by Robin P. Wharton and Gary Struhl. Authorship and experimental findings
A developmental biologist who studied developmental patterning through regulation of RNA and translation, including experiments on Bicoid and Caudal.[ref]
RNA recognition and translational regulation by a homeodomain protein by Josh Dubnau and Gary Struhl. Authorship and experimental findings
A developmental biologist who investigated translational regulation by Bicoid, connecting recognition of Caudal RNA sequences to developmental patterning.[ref]
RNA recognition and translational regulation by a homeodomain protein by Josh Dubnau and Gary Struhl. Authorship and experimental findings
A developmental biologist who studied cell polarity during Xenopus laevis gastrulation, distinguishing movement defects from changes in cell fate.[ref]
Dishevelled controls cell polarity during Xenopus gastrulation by John B. Wallingford and others. Authorship and experimental findings
A developmental biologist who investigated collective mesendoderm migration, testing how cell contacts communicate directionality during movement.[ref]
Collective mesendoderm migration relies on an intrinsic directionality signal transmitted through cell contacts by Julien G. Dumortier and others. Authorship and experimental findings
A developmental biologist who studied mechanical forces during epiboly, using flow and force measurements to test actomyosin-dependent tissue movement.[ref]
Forces driving epithelial spreading in zebrafish gastrulation by Martin Behrndt and others. Authorship and experimental findings
A developmental biologist who investigated the organization of the amphioxus Hox cluster and its implications for early chordate development.[ref]
Archetypal organization of the amphioxus Hox gene cluster by Jordi Garcia-Fernàndez and Peter W. H. Holland. Authorship and experimental findings
A developmental biologist who studied the amphioxus Hox cluster, using comparison to investigate ancestral chordate gene organization.[ref]
Archetypal organization of the amphioxus Hox gene cluster by Jordi Garcia-Fernàndez and Peter W. H. Holland. Authorship and experimental findings
A developmental biologist who investigated Hox cluster organization and expression in ray-finned fish, comparing retention and loss after genome duplication.[ref]
Developmental Roles of Pufferfish Hox Clusters and Genome Evolution in Ray-Fin Fish by Angel Amores and others. Authorship and experimental findings
A developmental biologist who studied dispersed Hox genes in Oikopleura dioica, testing the relationship between physical gene order and order of expression.[ref]
Hox cluster disintegration with persistent anteroposterior order of expression in Oikopleura dioica by Hee-Chan Seo and others. Authorship and experimental findings
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.
Figure 3. Visual Studio Code extension installation.
Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. 
- Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact