Topics (384k) Articles (398k) Users (410) Discussions (242) Comments (383) Files (13k) New article
A botanist who investigated how natural variation and dosage of HEI10 change genetic recombination in Arabidopsis thaliana.[ref]
A botanist who studied how changes in chromatin and DNA methylation affect chromosomal crossovers near centromeres.[ref]
A botanist who investigated how the wheat Ph1 locus affects chromosome synapsis and genetic recombination.[ref]
A botanist who studied species-wide diversity of NLR genes in Arabidopsis thaliana, extending the immune-receptor inventory beyond a single reference genome.[ref]
A botanist who investigated immune recognition by the RRS1-RPS4 receptor pair, including the role of an integrated decoy.[ref]
A botanist who studied hybrid necrosis caused by inappropriate immune activation, connecting plant immunity to incompatibility between genetic backgrounds.[ref]
-Portr_18163.jpg?width=260)
Portrait of Kirsten Bomblies
. Via Wikimedia Commons; credits and usage information are on the linked source file page. Source.A botanist who investigated how maternal temperature history, FLOWERING LOCUS T activity and progeny seed dormancy are connected.[ref]
Researcher in receptor biophysics. Manglik and collaborators investigated the dynamic process of beta-2-adrenergic receptor signaling, connecting structural states with transitions that a single static receptor model cannot fully describe.[ref]
Researcher in genetic recombination. Chen and collaborators investigated RecA bound to single- and double-stranded DNA, connecting molecular structures with the exchange of homologous DNA strands.[ref]
Mechanism of homologous recombination from the RecA–ssDNA/dsDNA structures by Zhucheng Chen and others. Author list and described study
Researcher in genetic recombination. Xu and collaborators studied human RAD51 filaments during strand exchange, connecting structures at different catalytic stages with the mechanism of homologous recombination.[ref]
Researcher in genetic recombination. Yang and collaborators investigated RecA–DNA synaptic and D-loop structures, connecting atomic organization with strand exchange between DNA molecules.[ref]
Mechanism of strand exchange from RecA–DNA synaptic and D-loop structures by Haijuan Yang and others. Author list and described study
Researcher in cryo-electron microscopy analysis. Zheng and collaborators developed MotionCor2 to correct beam-induced sample motion, connecting image alignment with preservation of high-resolution structural information.[ref]
Researcher in structural biology. Nakane and collaborators demonstrated single-particle cryo-electron microscopy at atomic resolution, connecting instrumental and analytical improvements with more detailed molecular interpretation.[ref]
Single-particle cryo-EM at atomic resolution by Takanori Nakane and others. Author list and described study
Researcher in structural biology. Yip and collaborators investigated atomic-resolution protein structure determination by cryo-electron microscopy, connecting improved imaging performance with the visibility of fine molecular detail.[ref]
Atomic-resolution protein structure determination by cryo-EM by Ka Man Yip and others. Author list and described study
Researcher in computational structural biology. Scheres developed RELION, connecting Bayesian inference with reconstruction of molecular structures from cryo-electron microscopy images.[ref]
Researcher in membrane structural biology. Murakami and collaborators determined multidrug-transporter structures supporting a functionally rotating mechanism, connecting different molecular conformations with stages of a transport cycle.[ref]
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.
Figure 3. Visual Studio Code extension installation.
Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. 
- Infinitely deep tables of contents:
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All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact