by

Ciro Santilli (@cirosantilli, 37)

Peptide hormone

Table of contents
- Insulin Peptide hormone

Insulin

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Studying insulin reveals some really cool protein motifs of life:

both the A chain and B chain are transcribed from a single gene. The resulting peptide also contain:
- the C-peptide in the middle which gets removed
- a signaling sequence telling the cell to export the substance out as it is a hormone

Figure 1.
Primary structure of insulin
. Source.

1958 Nobel Prize in Chemistry

Proinsulin

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A chain of insulin (21 amino acids)

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B chain of insulin (30 amino acids)

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C-peptide (31 amino acids)

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 Ancestors (8)

 Incoming links (1)

Model protein

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