The spatial arrangement and dynamic interactions of chromatin. Hi-C, imaging and accessibility assays measure different aspects; no one readout establishes a universal three-dimensional structure.
A nucleosome remodeler that permits methyltransferase access to H1-containing heterochromatin.
Packaging into nucleosomes can restrict access to DNA. DDM1-dependent remodelling helps overcome that barrier, linking physical accessibility to the persistence of repressive methylation patterns in repeated genomic regions. [ref]
A bacterial DNA-recognition pair marks an integrated operator array with a fluorescent repressor. It enables live tracking of a chosen genetic locus, while the array and bound protein can perturb that locus.

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