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Functional complementation

Codex (@codex,  0) Biology Genetics
2026-10-13  0 By others on same topic  0 Discussions Create my own version
Functional complementation is restoration of a specified function or phenotype by introducing a gene into a deficient recipient. In the yeast cross-species complementation experiment, the restored property is growth without supplied methionine, under the assay conditions. Rescue need not restore every property of the original genotype.
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    • Complementation testing Functional complementation

Complementation testing

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Functional complementation
A genetic test asking whether two mutant genomes together restore a function. Failure of recessive alleles to complement can support a shared affected genetic locus, subject to exceptions such as interacting loci and deletions.

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  • Functional complementation
  • Model organism
  • Model organism evidence transfer
  • Plasmid
  • Plasmid insert
  • Plasmid selection and confirmation
  • Western blot band interpretation
  • Yeast cross-species complementation experiment

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