Melvin P. Judkins was a radiologist who developed preshaped catheters and a percutaneous transfemoral method for selective coronary angiography. His work connected catheter geometry, vascular anatomy and X-ray recording: the instrument had to reach a particular arterial opening, while the imaging system had to record the contrast-filled vessels.[ref]
His 1967 report Selective Coronary Arteriography: Part I: A Percutaneous Transfemoral Technic by Melvin P. Judkins described 100 consecutive patients examined for suspected coronary disease. Both coronary arteries were selectively catheterized from femoral access, and contrast injections were recorded by direct serial radiography and cine imaging. The methods describe forming catheter shapes over preformed bending wires, showing that the instrument's geometry was an engineered part of the measurement rather than an incidental tube.[ref]
For an illustrative contrast experiment, imagine comparing a broad injection upstream with a small injection at the opening of one branch. The latter changes where contrast first enters and can make the selected branch easier to distinguish. That qualitative comparison explains the word selective; it does not specify a safe injection protocol or claim equal performance in every anatomical arrangement.
Judkins also collaborated with Charles T. Dotter on transluminal treatment of arterial obstruction, linking diagnostic access to the possibility of treatment through a catheter.[ref] His preshaped coronary instruments and the joint obstruction work are related contributions, but they address different immediate tasks: delineating a vessel and changing an obstructed passage.

Tagged

Charles T. Dotter was a radiologist whose work helped establish interventional radiology: using imaging-guided vascular access to treat disease as well as visualize it. His Oregon institution credits his 1964 percutaneous transluminal angioplasty with launching that approach. With Melvin P. Judkins, he reported the development of catheter-based treatment for arterial obstruction.[ref][ref]
The motivating observation was mechanical as well as radiological. Their 1965 report discussed catheter pathways through or alongside obstructed arterial material and illustrated contrast visualization of such passages. An event that could complicate diagnostic catheterization suggested that a new flow path might also be deliberately useful. The report framed the approach as a treatment for obstruction, rather than merely a way to obtain a sharper radiograph.[ref]
A separate idealized flow calculation explains why lumen size matters. For a long circular tube carrying steady laminar flow of a Newtonian fluid, with fixed pressure difference, length and viscosity, flow is proportional to the fourth power of the radius. Increasing the radius by a factor of two would increase this model's flow by . Real blood vessels are compliant, flow can be pulsatile and lesions have complicated shapes; the calculation is an explanatory limit, not an outcome predicted for a particular patient.
Dotter's contribution illustrates a scientific change of question: imaging can measure where a passage is obstructed, while an instrument introduced under imaging guidance can alter that passage. Demonstrating instrument passage, restoring flow and establishing durable clinical benefit are distinct evidential steps. The historical report motivates this sequence without making them equivalent.

Tagged

N. J. Pelc is a coauthor with D. R. Enzmann of a 1991 study that used phase-contrast magnetic resonance imaging to measure cerebrospinal fluid motion through the cardiac cycle. The work illustrates how magnetic resonance imaging can provide a time-dependent physiological measurement rather than only an anatomical picture.[ref]
The investigators studied ten healthy volunteers and four patients whose conventional magnetic-resonance images were normal. Peripheral cardiac gating divided the measurement into 16 flow-encoded images per cycle. The flow encoding distinguished opposite directions of cerebrospinal fluid motion, and measurements at several locations showed that the timing of the motion differed between the ventricular system and surrounding spaces.[ref]
For an illustrative one-second cycle, 16 equally spaced phases would separate samples by seconds. The paper's number of cardiac phases therefore matters: an average over the entire cycle could hide changes of direction within it. Conversely, sixteen phases are a temporal sampling scheme, not evidence of sixteen independent subjects. This example explains the measurement design without assigning an unreported individual contribution to either coauthor.
The study examined ten healthy volunteers and four patients whose conventional MR images were normal. Peripheral gating produced sixteen quantitative flow-encoded images over the cardiac cycle. Measurements distinguished the timing of fluid motion in ventricular and subarachnoid spaces, demonstrating why static anatomy alone does not describe pulsatile movement.[ref]
The methodological contribution is an example of turning image contrast into a physiological measurement. Direction-sensitive signals and repeated sampling across a heartbeat distinguish oscillatory motion from a compartment that simply looks fluid-filled. The reported display convention assigned opposite intensities to opposite craniocaudal directions; that convention belongs to the acquisition and is not a universal rule for brightness in every MR image.
The initials are retained as verified in the original research record. The paper establishes authorship and the reported results; it does not separately document which apparatus component or analysis step each coauthor personally performed.

Tagged

Articles by others on the same topic (0)

There are currently no matching articles.