Use the unbiased sample covariance matrix
and assume is positive-definite and , so is invertible almost surely. For a nonzero fixed direction , the observations have mean and variance . Their squared Student t-test statistic for the projected null mean is
Put . The Cauchy-Schwarz inequality gives
with equality when is proportional to , if . For every projected statistic is zero. Maximizing the squared discrepancy over directions therefore gives Hotelling's T-squared statistic:
This uses the squared generalized Rayleigh quotient. The preliminary formula on the printed cover has an unsquared numerator and is not valid as written: setting makes that ratio for , so it is unbounded. The displayed Cauchy-Schwarz argument supplies the needed corrected identity independently.
Under the null, let and . Then , , and are independent. To see these sample properties, apply an orthogonal transformation to the observation indices with first row . Its first centered row is ; its other rows are independent residual contrasts, independent of the first. Their outer products sum to , establishing the Wishart distribution and independence.
Since , use the supplied Gaussian-Wishart quadratic-form law with to obtain
Thus a level- test rejects when this scaled statistic exceeds the quantile of the F-distribution. The Gaussian-Wishart law requires independence; it holds here because of the orthogonal sample decomposition. Its printed use of instead of the introduced is a notational slip. A fixed-direction Student law alone would not calibrate the maximized statistic, because its maximizing direction depends on the sample.
Transform each observation to . If has full row rank , the transformed sample is multivariate normal with mean and positive-definite covariance matrix . Its sample mean is and its unbiased sample covariance matrix is . The Hotelling test of linear hypotheses therefore uses
Here is required. Reject for a large scaled statistic using the relevant upper F-distribution quantile. If the rows of are dependent, choose a basis for their row space, use that basis as the contrast matrix, and replace by its rank . The null hypothesis is unchanged, but redundant contrasts must not be treated as independent dimensions. Rank zero gives no restrictions and hence no nontrivial test.
At equal spacing , the adjacent increments of an affine mean profile are all . Their differences are therefore zero. Define the matrix whose row associated with the interior time has coefficients in columns . Then
Conversely these equations make all adjacent first differences equal, so is affine in , equivalently affine in the equally spaced times. Thus the restriction is exactly , not just a necessary condition. Its null space has basis and , so has rank .
For and , the second-difference test of a linear mean profile is the Hotelling test of linear hypotheses with
Reject the affine-profile hypothesis when the scaled statistic exceeds its level- upper F-distribution critical value. This removes the nuisance intercept and slope without estimating them separately.
For unequal ordered distinct times, put and replace each second-difference row by the adjacent-slope contrast
Its three coefficients are , and . Vanishing means all adjacent slopes agree, again giving null space and rank . Use this new in the same statistic and null distribution. For , every mean profile at distinct times is affine, so there is no lack-of-linearity restriction to test.

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