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With the travelling wave coordinate $\xi =x-ct$, the reaction-diffusion system becomesAt the advancing leading edge the healthy-tissue density is small. Put $f(\xi )\sim e^{-\lambda \xi }$ with $\lambda >0$. The linearization at $f=0$ givesso a nonoscillatory decaying front requires real positive roots,The pulled travelling front selects the Fisher-KPP minimum wave speed, and therefore

For the initial wound $0<x<W$, two mirror-image fronts enter from its endpoints. The left front moves right from $x=0$ and the right front moves left from $x=W$, each with speed approximately $c_{\min }$. A sequence of sketches would show the initial rectangular depression becoming two smooth monotone transition layers, the zero-density plateau shrinking, and the two layers meeting near $x=W/2$ before the profile relaxes to $S=1$. Their meeting time isThere is an additional local relaxation time of order $1/r$ if “close to one” is assigned a fixed numerical tolerance, so the displayed estimate is the dominant healing time when $W$ is large compared with the front width $\sqrt{D/r}$.

Write the reaction terms asA nonzero homogeneous equilibrium satisfies $v_{\ast }=\beta u_{\ast }$ and $1+u_{\ast }-\gamma v_{\ast }=0$, henceFor physically positive populations it exists exactly when

The reaction Jacobian matrix at this equilibrium isIts trace and determinant areThe equilibrium is therefore stable to spatially uniform perturbations when

For a spatial Fourier mode of wavenumber $k$, put $q=k^2$. The linearized reaction-diffusion system has matrixIts trace is smaller than $\mathrm{tr}J$, whileThe two-species diffusion-driven instability criterion says that this upward-opening quadratic becomes negative for some $q>0$ precisely whenCombining all conditions, a Turing instability may occur in the region

At onset the discriminant vanishes, and the double root isThe threshold relation givesso the critical wavenumber isIf $d=1$, uniform stability requires $\beta >1$ whereas diffusion-driven instability requires $d>\beta$. These inequalities are incompatible, so the Turing region vanishes.

A spatially homogeneous equilibrium of a reaction-diffusion system is a constant state $u_{\ast }$ satisfying $f(u_{\ast })=0$. Since its spatial derivatives vanish, its stability to homogeneous perturbations is determined by the Jacobian matrix $Df(u_{\ast })$; diffusion can additionally destabilize nonconstant modes.