Oxford Nanopore MinION by Ciro Santilli 37 Updated 2025-07-16
One of the sequencers made by Oxford Nanopore Technologies.
The device has had several updates since however, notably of the pore proteins which are present in the critical flow cell consumable.
Official documentation: nanoporetech.com/products/minion (archive)
Figure 5.
Oxford nanopore MinION flow cell package.
Source.
Figure 6.
Oxford nanopore MinION flow cell front.
Source.
Figure 7.
Oxford nanopore MinION flow cell back.
Source.
Figure 8.
Oxford nanopore MinION flow cell pipette loading.
Source.
Figure 9.
Oxford Nanopore MinION connected to a Mac via USB.
Source.
Video 1.
Oxford Nanopore MinION software channels pannel on Mac.
Source.
At the time of the experiment, Illumina equipment was cheaper per base pair and dominates the human genome sequencing market, but it required a much higher initial investment for the equipment (TODO how much).
The reusable Nanopore device costs just about 500 dollars, and about 500 dollars (50 unit volume) for the single usage flow cell which can decode up to 30 billion base pairs, which is about 10 human genomes 1x! Note that 1x is basically useless for one of the most important of all applications of sequencing: detection of single-nucleotide polymorphisms, since the error rate would be too high to base clinical decisions on.
Compare that to Illumina which is currently doing about an 1000 dollar human genome at 30x, and a bit less errors per base pair (TODO how much).
Other advantages of the MinION over Illumina which didn't really matter to this particular experiment are:
Master's degree by Ciro Santilli 37 Updated 2025-07-16
In your normal 2020 broken educational system, it is the first time at which students get an official chance to learn something advanced, and possibly prepare to go venture into the PhD desert.
University entry exam by Ciro Santilli 37 Updated 2025-07-16
These are the most evil examinations society has.
They mean that until you are 18, you have to study a bunch of generic crap you hate just to get into university. Rather than studying whatever it is that you truly love to become a God at it as fast as possible and have any chance of advancing the field.
And then, if you decide that you want to change, which is not unlikely since you haven't really try to study what you signed up for before then, it can be very hard and time consuming, leading to a bunch of adults with useless degress they will never use at work.
With the invention of the Internet, all teaching material can be free and open source. Only laboratory space has any cost (besides the opportunity cost of participation in actual projects in a research team).
Per-country list: en.wikipedia.org/wiki/List_of_admission_tests_to_colleges_and_universities
archive.ph/GpyQv#selection-925.340-925.495 Reagan's OMB Director David Stockman told congress:
students are "tax eaters... [and] a drain and drag on the American economy." Student aid "isn’t a proper obligation of the taxpayer,"
and then:
In fact, voters were far more likely to punish lawmakers for raising taxes. Elected officials made the political calculus that it was safer politically to divert existing funds from discretionary costs to mandatory costs like health care, prisons and primary education, than raise taxes.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
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    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
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    Figure 2.
    You can publish local OurBigBook lightweight markup files to either https://OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
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All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact