safe superintelligence inc. by Ciro Santilli 37 Created 2025-03-17 Updated 2025-07-16
raised $1b at $5b valuation on september 2024, then $2b at $30b on march 2025. lol!
From their website:
Superintelligence is within reach.
Our singular focus means no distraction by management overhead or product cycles, and our business model means safety, security, and progress are all insulated from short-term commercial pressures.
Dynein by Ciro Santilli 37 Created 2025-03-17 Updated 2025-07-16
Kinesin by Ciro Santilli 37 Created 2025-03-17 Updated 2025-07-16
Video 2.
Kinesin Motor Protein 3D Animation by Art of the cell
. Source.
Actin by Ciro Santilli 37 Created 2025-03-17 Updated 2025-07-16
Microtubule motors by Ciro Santilli 37 Created 2025-03-17 Updated 2025-07-16
There are two families:
  • kinesin moves in one direction
  • dynein moves in the other direction
Myosin by Ciro Santilli 37 Created 2025-03-17 Updated 2025-07-16
Family of proteins that walks on actin microfilaments.
Responsible for muscle contraction.
Microtubule by Ciro Santilli 37 Created 2025-03-17 Updated 2025-07-16
Microfilament by Ciro Santilli 37 Created 2025-03-17 Updated 2025-07-16
Motor protein by Ciro Santilli 37 Created 2025-03-17 Updated 2025-07-16
Video 1.
A Day in the Life of a Motor Protein by Hoogenraad Lab
. Source.
Nucleic acid double helix by Ciro Santilli 37 Created 2025-03-17 Updated 2025-07-16
Muscle contraction by Ciro Santilli 37 Created 2025-03-17 Updated 2025-07-16
Power, Sex, Suicide by Nick Lane (2006) page 53 suggests that one tremendous advantage of eukaryotes over bacteria is their ability to change shape due to the presence of the cytoskeleton, and the lack of a rigid bacterial cell wall.
Imagine in a world where there are only bacteria, and you can eat entire bacteria in one go, what a huge advantage that is!
Structure of DNA by Ciro Santilli 37 Created 2025-03-17 Updated 2025-07-16
Zero-knowledge proof by Ciro Santilli 37 Created 2025-03-17 Updated 2025-07-16
Video 1.
I can prove I've solved this Sudoku without revealing it by Polylog
. Source.
Deutsche Welle by Ciro Santilli 37 Created 2025-03-17 Updated 2025-07-16
James Watson by Ciro Santilli 37 Created 2025-03-17 Updated 2025-07-16
He was the nerdy one of the dynamic duo.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either https://OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact