Died of cancer at age 53. Ciro Santilli just can't help but speculate that it is linked to radioactivity exposure.
Taboola is a clickbait trained neural network. Which happens to have been written by Adolf Hitler.
The by far dominating DNA sequencing company of the late 2000's and 2010's due to having the smallest cost per base pair.
To understand how Illumina's technology works basically, watch this video: Video 1. "Illumina Sequencing by Synthesis by Illumina (2016)".
The key innovation of this method is the Bridge amplification step, which produces a large amount of identical DNA strands.
Pick few good bets and invest enough on them by
Ciro Santilli 35 Updated 2025-01-29 +Created 1970-01-01
Poor countries don't have a lot of money.
Therefore, you have to pick a few key the next big thing deep tech bets, and invest on those enough.
These have to be few, because your country is poor, and so you can't invest on everything.
Therefore, the bets have to be well selected, because it is useless to make several insufficient investments: you have to pick a few ones, and put enough time and money into each one of them for them to stand any chance. These bets should be made and reevaluated on 5/10 year horizons.
The key things that you have to select are:
- which poor students you will bet on educating. Since you can't give amazing education to everyone, you have to select the most promising poor students somehow, and give those free amazing learning conditions: free gifted education
- which ares to focus on. Ciro believes that molecular biology technologies and quantum computing would be good bets. Focusing on the previous next big things, e.g. classic computers, is always a losing bet on average
And then you only tax those companies heavily when the start to bring in real money. These are startups remember! You only need 5 unicorns a year to call it a success. And countries should not be greedy and invest through equity, but rather recoup their investment through taxation alone.
Ciro's second removed uncle, who was a physicist at the University of Campinas, one of the best universities in the country, told him an anecdote. He had moved from fusion energy research to solar cell research. At some point, there was a research lab that needed 10 million to buy a machinery critical for their experiment. They asked and asked, and finally the government gave them only 2 million. So in the end they spent those 2 million in random ways, but of course did not achieve their research goal and no money came out of it.
He also explained how as a result of the insufficient investments, he felt clearly that some of the semiconductor production facilities related to solar power he saw simply were not able to control the production process adequately to produce consistent silicon. As a result, everything failed sooner or later as people found more and more bugs that they did not have the time to solve.
Another key investment is enticing back experienced exchange-students who have learnt new techniques to be heads of laboratory/founders to back in your country.
A fantastic initiative from Brazil for example is BRASA, which aims to put together Brazilian exchange students to make a difference back in Brazil.
Do not try to forbid external companies from selling in your country. Instead, fund your own companies to be able to fight the external market off. And if they can't, let them die and pick a different bet. Video "How Taiwan Created TSMC by Asianometry (2020)" has a good mention. Protectionism is something that Brazil notably tried to do, and look at what it led, not a single international success.
github.com/deepmind/lab/tree/master/game_scripts/levels/contributed/dmlab30 has some good games with video demos on YouTube, though for some weird reason they are unlistd.
TODO get one of the games running. Instructions: github.com/deepmind/lab/blob/master/docs/users/build.md. This may helpgithub.com/deepmind/lab/issues/242: "Complete installation script for Ubuntu 20.04".
It is interesting how much overlap some of those have with Ciro's 2D reinforcement learning games
The games are 3D, but most of them are purely flat, and the 3D is just a waste of resources.
City of Light: The Story of Fiber Optics by
Ciro Santilli 35 Updated 2025-01-29 +Created 1970-01-01
The book is a bit slow until Charles K. Kao comes along, then it gets exciting.
This section discusses the pre-photon understanding of the polarization of light. For the photon one see: photon polarization.
polarization.com/history/history.html is a good page.
People were a bit confused when experiments started to show that light might be polarized. How could a wave that propages through a 3D homgenous material like luminiferous aether have polarization?? Light would presumably be understood to be analogous to a sound wave in 3D medium, which cannot have polarization. This was before Maxwell's equations, in the early 19th century, so there was no way to know.
Pinned article: ourbigbook/introduction-to-the-ourbigbook-project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivative - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.Figure 3. Visual Studio Code extension installation.Figure 4. Visual Studio Code extension tree navigation.Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.Video 4. OurBigBook Visual Studio Code extension editing and navigation demo. Source. - Internal cross file references done right:
- Infinitely deep tables of contents:
Figure 6. Dynamic article tree with infinitely deep table of contents.Live URL: ourbigbook.com/cirosantilli/chordateDescendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact