The by far dominating DNA sequencing company of the late 2000's and 2010's due to having the smallest cost per base pair.

Illumina actually bought their 2010's dominating technology from a Cambridge company called Solexa.

To understand how Illumina's technology works basically, watch this video: Video 1. "Illumina Sequencing by Synthesis by Illumina (2016)".

The key innovation of this method is the Bridge amplification step, which produces a large amount of identical DNA strands.

This is one of the the key innovations of the Illumina (originally Solexa) sequencing.

This step is genius because sequencing is basically a signal-to-noise problem, as you are trying to observe individual tiny nucleotides mixed with billions of other tiny nucleotides.

With bridge amplification, we group some of the nucleotides together, and multiply the signal millions of times for that part of the DNA.

They put a lot of emphasis into base calling. E.g.:

Red clump stars are a specific type of red giant star in the later stages of stellar evolution. These stars are typically in the horizontal branch phase, which follows the giant phase of a star's life cycle. Red clump stars represent a phase where stars have exhausted the hydrogen in their cores and are now fusing helium into carbon and oxygen. They are somewhat hotter and brighter than ordinary red giants, and their spectra show strong absorption lines indicative of helium fusion.

Exoplanets detected by radial velocity, also known as the Doppler method or the radial velocity method, is a technique used to identify exoplanets by observing the gravitational influence they have on their host stars. This method takes advantage of the Doppler effect, where the light emitted by a star shifts in wavelength depending on its motion relative to an observer.

Collisional excitation is a process in which an atom or molecule absorbs energy during a collision with a particle, such as another atom, molecule, or electron. This energy transfer can promote an electron within the atom or molecule to a higher energy state, or excited state. Here's how it works: 1. **Encounter**: During a collision, kinetic energy from the colliding particle (which can be a gas particle or an electron) is transferred to the target atom or molecule.

The Deslandres table, also known as the Deslandres chart, is a tool used in the field of astronomy and astrophysics to facilitate the classification and analysis of celestial bodies' spectra, particularly stars. Named after the French astronomer Camille Deslandres, the table organizes spectral lines based on their wavelengths. In detail, the Deslandres table presents a systematic arrangement of the absorption or emission lines observed in the spectra of stars.

The term "diffuse series" can refer to different concepts depending on the context. However, it is not a widely recognized term in any specific field, such as mathematics, physics, or biology. It might be a misinterpretation or a specific concept within a niche area that is not broadly known.

The Ellis R. Lippincott Award is an honor presented by the American Association of Law Libraries (AALL). It recognizes significant contributions to the field of legal information and law librarianship, typically through excellence in legal research, teaching, and the development of legal information resources. Named after a prominent figure in law librarianship, the award underscores the importance of innovation, leadership, and dedication in legal information services.

Fluorescence spectroscopy is an analytical technique used to measure the fluorescence emitted by a substance after it has absorbed light or other electromagnetic radiation. This technique is based on the principle of fluorescence, where certain molecules (fluorophores) absorb light at a specific wavelength and subsequently emit light at a longer wavelength.

The GF method, or the Galerkin Finite Element method, is a numerical technique used for solving differential equations, particularly in the fields of engineering and applied mathematics. It is a type of finite element method (FEM) that combines the Galerkin method—which is a technique for converting a continuous problem (like a differential equation) into a discrete one—with the finite element analysis framework.

Gamma spectroscopy is an analytical technique used to measure and analyze the energy and intensity of gamma-ray radiation emitted by radioactive materials. This method is widely utilized in various fields, including nuclear physics, environmental monitoring, medical diagnostics, and radioactive waste management, among others. ### Key Concepts of Gamma Spectroscopy: 1. **Gamma Rays**: Gamma rays are high-energy electromagnetic radiation emitted during radioactive decay. They have no mass or charge, making them highly penetrating and difficult to shield.

A blue dwarf is a theoretical type of star that would occur at the end of the main sequence phase of red dwarfs in the far future. Red dwarfs are the smallest and coolest type of main-sequence stars. They burn their hydrogen at a low rate and can have lifespans that last for tens to hundreds of billions of years, far exceeding that of larger stars, which typically evolve into more massive stages like red giants.

A common envelope jets supernova refers to a specific type of supernova explosion associated with binary star systems, particularly those involving a white dwarf and a companion star. In this scenario, the two stars orbit each other closely, and as they evolve, the outer layers of one star can transfer mass to the other via an unstable mass transfer, leading to a "common envelope" phase.

A Thorne–Żytkow object (TZO) is a hypothetical type of astronomical object that is a unique combination of a neutron star and a red giant star. This concept arises from theoretical studies in astrophysics and is named after physicists Kip Thorne and Edward Żytkow, who proposed the idea in the 1970s.