www.lgcstandards-atcc.org/products/all/49896.aspx:
- £355.00 in 2019
- biosafety level: 2
Size: 300 x 600 nm
Reproduction time: www.quora.com/unanswered/How-long-do-Mycoplasma-bacteria-take-to-reproduce-under-optimal-conditions
Has one of the smallest genomes known, and JCVI made a minimized strain with 473 genes: JCVI-syn3.0.
The reason why genitalium has such a small genome is that parasites tend to have smaller DNAs. So it must be highlighted that genitalium can only survive in highly enriched environments, it can't even make its own amino acids, which it normally obtains fromthe host cells! And because it cannot do cellular respiration, it very likely replicates slower than say E. Coli. It's easy to be small in such scenarios!
Power, Sex, Suicide by Nick Lane (2006) section "How to lose the cell wall without dying" page 184 has some related mentions puts it well very:
One group, the Mycoplasma, comprises mostly parasites, many of which live inside other cells. Mycoplasma cells are tiny, with very small genomes. M. genitalium, discovered in 1981, has the smallest known genome of any bacterial cell, encoding fewer than genes. Despite its simplicity, it ranks among the most common of sexually transmitted diseases, producing symptoms similar to Chlamydia infection. It is so small (less than a third of a micron in diameter, or an order of magnitude smaller than most bacteria) that it must normally be viewed under the electron microscope; and difficulties culturing it meant its significance was not appreciated until the important advances in gene sequencing in the early 1990s. Like Rickettsia, Mycoplasma have lost virtually all the genes required for making nucleotides, amino acids, and so forth. Unlike Rickettsia, however, Mycoplasma have also lost all the genes for oxygen respiration, or indeed any other form of membrane respiration: they have no cytochromes, and so must rely on fermentation for energy.
Downsides mentioned at youtu.be/PSDd3oHj548?t=293:
- too small to see on light microscope
- difficult to genetically manipulate. TODO why?
- less literature than E. Coli.
Data:
- www.ncbi.nlm.nih.gov/bioproject/97 contains genome, genes, proteins.
- www.genome.jp/kegg-bin/show_pathway?mge01100 all known pathways. TODO: numerical reaction coefficients? Which enzyimes mediate what? Appears to factor pathways across organisms, which is awesome.
There's no point.
The question remains there, but people lose the ability to help the asker.
Reputation is meaningless regardless, since JavaScript gurus will always have 1000x more readers than low level junkies.
The deeper problem: the existence of multiple separate websites instead of just using the tags on a single website.
Examples:
Just add GDB Dashboard, and you're good to go.
Official demos: github.com/KhronosGroup/glTF-Sample-Assets These are visible at: github.khronos.org/glTF-Sample-Viewer-Release/ with a JavaScript viewer present at: github.com/KhronosGroup/glTF-Sample-Viewer TODO can you load models on the web?
Supports animations, e.g.:
gltf-viewer.donmccurdy.com/ is based on doesn't work with those examples because they have separate asset files.
f3d just worked for it.
On the Relative Motion of the Earth and the Luminiferous Ether Updated 2025-01-10 +Created 1970-01-01
This paper is in the public domain and people have uploaded it e.g. to glorious Wikisource: en.wikisource.org/wiki/On_the_Relative_Motion_of_the_Earth_and_the_Luminiferous_Ether including its amazing illustrations.
Pinout overview: makecode.microbit.org/device/pins Basically 0, 1, and 2 are the truly generic ones. They can also serve as ADCs.
Micropython documentation: microbit-micropython.readthedocs.io/en/latest/pin.html
A Drosophila melanogaster has about 135k neurons, and we only managed to reconstruct its connectome in 2023.
The human brain has 86 billion neurons, about 1 million times more. Therefore, it is obvious that we are very very far away from a full connectome.
Instead however, we could look at larger scales of connectome, and then try from that to extract modules, and then reverse engineer things module by module.
This is likely how we are going to "understand how the human brain works".
Some notable connectomes:
- 2019: 1mm cube of mouse brain: www.nature.com/articles/d41586-019-02208-0
- 2023: Drosophila connectome
This game (1 or 2, can't remember) made an impression on Ciro Santilli for some reason.
Only many many years after playing it, after Ciro started getting more interested, did he learn that it was actually an adaptation of the Chinese mega-classic Water Margin.
"Suikoden" is the actual Japenese transliteration for the Chinese name of the original Water Margin novel.
Yet another case of Chinese thing better known in the West as Japanese.
The game puts great emphasis on the concept of the 108 Stars of Destiny, which never left Ciro's mind: making 108 allies, the main collectible of the game, allows you to make a more powerful alliance, and unlock better endings.
This is a general philosophy that Ciro Santilli, and likely others, observes over and over.
Basically, continuity, or higher order conditions like differentiability seem to impose greater constraints on problems, which make them more solvable.
Some good examples of that:
- complex discrete problems:
- simple continuous problems:
- characterization of Lie groups
In 2020 Brazil for example, you are not allowed in theory to obtain a double nationality which you were not allowed to have as a birth right.
This means that Brazilian students e.g. in France, many of whom could easily obtain the French citizenship had to either chose between:Can you guess which option Brazilian students would usually pick?
- giving up their Brazilian citizenship. Who the fuck would do that? Brazilians love their country despite all!
- not getting French citizenship. This meant in France having to come 6 AM once a year to some police station on some suburbia to stamp a piece of paper, plus having your VISA completely dependant on your employer for several years until you could obtain a permanent VISA, making it very hard to change jobs, and putting you in a constantly precarious position
- keeping both citizenships, ignoring Brazilian law, which is extremely unlikely to sue you anyways for this bullshit law, and just hope for the best
As a poor country, you have to allow people to obtain multiple citizenship. Students are not going to go back because they don't have the foreign citizenship. They are just going to have to ensure shittier jobs for a few years, thus diminishing the chances that they will actually lean anything useful to bring back to your country later on.
Claimed to remove metadata from servers unless legally obliged to collect it: www.quora.com/Does-WhatsApp-store-messages-on-its-servers-or-is-all-deleted-after-delivery-and-only-stored-on-recipients-phones/answer/Ciro-Santilli
They've had a few breaches: www.whatsapp.com/security/advisories/
They claim to delete metadata: www.quora.com/Does-WhatsApp-store-messages-on-its-servers-or-is-all-deleted-after-delivery-and-only-stored-on-recipients-phones/answer/Ciro-Santilli
WhatsApp founder Jan Koum talks about their Journey by Roots (2017)
Source. Good talk, explains how everything happened in the perfect location at the perfect time: unemployed people who knew how to code, bought an iPhone, the next big platform, at its very beginning, they had just release the required push notifications API, and he travelled a lot and knew how much SMS sucked, especially international.Official support is abysmal, very focused on MicroPython and their graphical UI.
The setup impossible to achieve as it requires setting up the Yotta, just like the impossible to setup Compile MicroPython code for Micro Bit locally on Ubuntu 22.04 with your own firmware setup.
So we just use github.com/lancaster-university/microbit-samples + github.com/carlosperate/docker-microbit-toolchain:.hex file size for the hello world was 447 kB, much better than the MicroPython hello world downloaded from the website which was about 1.8 MB!
docker pull ghcr.io/carlosperate/microbit-toolchain:latest
git clone https://github.com/lancaster-university/microbit-samples
cd microbit-samples
git checkout 285f9acfb54fce2381339164b6fe5c1a7ebd39d5
# Select a sample, builds one at a time. The default one is the hello world.
cp source/examples/hello-world/* source
# Build and flash.
docker run -v $(pwd):/home --rm ghcr.io/carlosperate/microbit-toolchain:latest yotta build
cp build/bbc-microbit-classic-gcc/source/microbit-samples-combined.hex "/media/$USER/MICROBIT/"If you try it again for a second time from a clean tree, it fails with:presumably because after Yotta died it started using GitHub as a registry... sad. When will people learn. Apparently we were at 5000 API calls per hour. But if you don't clean the tree, you will be just fine.
warning: github rate limit for anonymous requests exceeded: you must log inpubmed.ncbi.nlm.nih.gov/27185558/ A Eukaryote without a Mitochondrial Organelle by Karnkowska et. al (2016)
There are unlisted articles, also show them or only show them.