The Alan Turing Institute Updated +Created
Inria Updated +Created
They do some really fun hardcore mathy stuff over there!
Ciro Santilli interned at Inria Centre at Université Côte d'Azur in the early 2010's. It was a disaster, largely his own fault, but also due to our broken educational system. But they do have awesome things as well.
Applied mathematics research institute Updated +Created
lenet Updated +Created
This is a small fork of activatedgeek/LeNet-5 by Ciro Santilli adding better integration and automation for:
Install on Ubuntu 24.10:
sudo apt install protobuf-compiler
cd lenet
virtualenv -p python3 .venv
. .venv/bin/activate
pip install -r requirements-python-3-12.txt
Download and extract MNIST train, test accuracy, and generate the ONNX lenet.onnx:
./train.py
Extract MNIST images as PNG:
./extract_pngs.py
Infer some individual images using the ONNX:
./infer.py data/MNIST/png/test/0/*.png
Draw on a GUI and see live inference using the ONNX:
./draw.py
TODO: the following are missing for this to work:
safe superintelligence inc. Updated +Created
raised $1b at $5b valuation on september 2024, then $2b at $30b on march 2025. lol!
From their website:
Superintelligence is within reach.
Our singular focus means no distraction by management overhead or product cycles, and our business model means safety, security, and progress are all insulated from short-term commercial pressures.
Dynein Updated +Created
Kinesin Updated +Created
Video 2.
Kinesin Motor Protein 3D Animation by Art of the cell
. Source.
Microtubule vs Microfilament Updated +Created
Actin Updated +Created
Microtubule motors Updated +Created
There are two families:
  • kinesin moves in one direction
  • dynein moves in the other direction
Myosin Updated +Created
Family of proteins that walks on actin microfilaments.
Responsible for muscle contraction.
Microtubule Updated +Created
Microfilament Updated +Created
Motor protein Updated +Created
Video 1.
A Day in the Life of a Motor Protein by Hoogenraad Lab
. Source.
Nucleic acid double helix Updated +Created
Muscle contraction Updated +Created
1962 Nobel Prize in Physiology and Medicine Updated +Created
Application of DNA sequencing Updated +Created
Eukaryotes can do phagocytosis due to their cytoskeleton Updated +Created
Power, Sex, Suicide by Nick Lane (2006) page 53 suggests that one tremendous advantage of eukaryotes over bacteria is their ability to change shape due to the presence of the cytoskeleton, and the lack of a rigid bacterial cell wall.
Imagine in a world where there are only bacteria, and you can eat entire bacteria in one go, what a huge advantage that is!

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