Ciro Santilli @cirosantilli 37

UniProt entry: www.uniprot.org/uniprot/P0AD86.

NCBI gene entry: www.ncbi.nlm.nih.gov/gene/944742.

The first gene in the E. Coli K-12 MG1655 genome. Remember however that bacterial chromosome is circular, so being the first doesn't mean much, how the choice was made: Section "E. Coli genome starting point".

Part of E. Coli K-12 MG1655 operon thrLABC.

At only 65 bp, this gene is quite small and boring. For a more interesting gene, have a look at the next gene, e. Coli K-12 MG1655 gene thrA.

Does something to do with threonine.

This is the first in the sequence thrL, thrA, thrB, thrC. This type of naming convention is quite common on related adjacent proteins, all of which must be getting transcribed into a single RNA by the same promoter. As mentioned in the analysis of the KEGG entry for e. Coli K-12 MG1655 gene thrA, those A, B and C are actually directly functionally linked in a direct metabolic pathway.

We can see that thrL, A, B, and C are in the same transcription unit by browsing the list of promoter at: biocyc.org/group?id=:ALL-PROMOTERS&orgid=ECOLI. By finding the first one by position we reach; biocyc.org/ECOLI/NEW-IMAGE?object=TU0-42486.

Transcription factor for E. Coli K-12 MG1655 operon thrLABC as shown at biocyc.org/ECOLI/NEW-IMAGE?object=TU0-42486.

Note that this is very close to the "end" of the genome.

NCBI: www.ncbi.nlm.nih.gov/gene/948874

UniProt: www.uniprot.org/uniprot/P0A9Q1

TODO DNA assembly structure.

This is unlike atomic systems like trapped ion quantum computers, where each atom is necessarily exactly the same as the other.

From the 2020/2021 Oxford physics course handbooks we can determine the following structure:

Trinity term, the third and final term of each year, contains mostly revision from the previous two terms, after which students take their final exams, which basically account for their entire grade. Trinity is therefore a very tense part of the year for the students. After that they have summer holidays, until coming back for the next year of madness.

The official external course landing page: www.ox.ac.uk/admissions/undergraduate/courses/course-listing/physics. 2021 archive: web.archive.org/web/20221208212856/https://www.ox.ac.uk/admissions/undergraduate/courses/course-listing/physics) In those pages we see the rough structure, except that it does not have the course codes "A1" etc., and some courses are missing.

At web.archive.org/web/20221229021312/https://www2.physics.ox.ac.uk/sites/default/files/2011-06-03/course_v3_pdf_80151.pdf page 11 we can see the global course structure giving the two options, 3 year BA or 4 year Oxford physics masters:

Practical courses notes: www-teaching.physics.ox.ac.uk/

Some others with lecture notes:

Example where this level is sufficient: nodejs/sequelize/raw/parallel_update_async.js.

Membrane.

As shown at pubmed.ncbi.nlm.nih.gov/16877062/#&gid=article-figures&pid=fig-3-uid-2 has transmembrane domain.

The best way to learn about them as of 2020 is to Google into Know Your Meme.

The size of a set.

For finite sizes, the definition is simple, and the intuitive name "size" matches well.

But for infinity, things are messier, e.g. the size of the real numbers is strictly larger than the size of the integers as shown by Cantor's diagonal argument, which is kind of what justifies a fancier word "cardinality" to distinguish it from the more normal word "size".

The key idea is to compare set sizes with bijections.

If Ciro Santilli ever becomes rich, he's going to solve this with: website front-end for a mathematical formal proof system, promise.

They come up a lot in many contexts, e.g.: