The algorithm is completely analogous to Diffie-Hellman key exchange in that you efficiently raise a number to a power times and send the result over while keeping as private key.
The only difference is that a different group is used: instead of using the cyclic group, we use the elliptic curve group of an elliptic curve over a finite field.
Elliptic curves by Computerphile (2018)
Source. youtu.be/NF1pwjL9-DE?t=143 shows the continuous group well, but then fails to explain the discrete part.Variant of Diffie-Hellman key exchange based on elliptic curve cryptography.
Running:gives:
hd hello_world.o00000000 7f 45 4c 46 02 01 01 00 00 00 00 00 00 00 00 00 |.ELF............|
00000010 01 00 3e 00 01 00 00 00 00 00 00 00 00 00 00 00 |..>.............|
00000020 00 00 00 00 00 00 00 00 40 00 00 00 00 00 00 00 |........@.......|
00000030 00 00 00 00 40 00 00 00 00 00 40 00 07 00 03 00 |....@.....@.....|
00000040 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 |................|
*
00000080 01 00 00 00 01 00 00 00 03 00 00 00 00 00 00 00 |................|
00000090 00 00 00 00 00 00 00 00 00 02 00 00 00 00 00 00 |................|
000000a0 0d 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 |................|
000000b0 04 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 |................|
000000c0 07 00 00 00 01 00 00 00 06 00 00 00 00 00 00 00 |................|
000000d0 00 00 00 00 00 00 00 00 10 02 00 00 00 00 00 00 |................|
000000e0 27 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 |'...............|
000000f0 10 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 |................|
00000100 0d 00 00 00 03 00 00 00 00 00 00 00 00 00 00 00 |................|
00000110 00 00 00 00 00 00 00 00 40 02 00 00 00 00 00 00 |........@.......|
00000120 32 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 |2...............|
00000130 01 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 |................|
00000140 17 00 00 00 02 00 00 00 00 00 00 00 00 00 00 00 |................|
00000150 00 00 00 00 00 00 00 00 80 02 00 00 00 00 00 00 |................|
00000160 a8 00 00 00 00 00 00 00 05 00 00 00 06 00 00 00 |................|
00000170 04 00 00 00 00 00 00 00 18 00 00 00 00 00 00 00 |................|
00000180 1f 00 00 00 03 00 00 00 00 00 00 00 00 00 00 00 |................|
00000190 00 00 00 00 00 00 00 00 30 03 00 00 00 00 00 00 |........0.......|
000001a0 34 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 |4...............|
000001b0 01 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 |................|
000001c0 27 00 00 00 04 00 00 00 00 00 00 00 00 00 00 00 |'...............|
000001d0 00 00 00 00 00 00 00 00 70 03 00 00 00 00 00 00 |........p.......|
000001e0 18 00 00 00 00 00 00 00 04 00 00 00 02 00 00 00 |................|
000001f0 04 00 00 00 00 00 00 00 18 00 00 00 00 00 00 00 |................|
00000200 48 65 6c 6c 6f 20 77 6f 72 6c 64 21 0a 00 00 00 |Hello world!....|
00000210 b8 01 00 00 00 bf 01 00 00 00 48 be 00 00 00 00 |..........H.....|
00000220 00 00 00 00 ba 0d 00 00 00 0f 05 b8 3c 00 00 00 |............<...|
00000230 bf 00 00 00 00 0f 05 00 00 00 00 00 00 00 00 00 |................|
00000240 00 2e 64 61 74 61 00 2e 74 65 78 74 00 2e 73 68 |..data..text..sh|
00000250 73 74 72 74 61 62 00 2e 73 79 6d 74 61 62 00 2e |strtab..symtab..|
00000260 73 74 72 74 61 62 00 2e 72 65 6c 61 2e 74 65 78 |strtab..rela.tex|
00000270 74 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 |t...............|
00000280 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 |................|
00000290 00 00 00 00 00 00 00 00 01 00 00 00 04 00 f1 ff |................|
000002a0 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 |................|
000002b0 00 00 00 00 03 00 01 00 00 00 00 00 00 00 00 00 |................|
000002c0 00 00 00 00 00 00 00 00 00 00 00 00 03 00 02 00 |................|
000002d0 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 |................|
000002e0 11 00 00 00 00 00 01 00 00 00 00 00 00 00 00 00 |................|
000002f0 00 00 00 00 00 00 00 00 1d 00 00 00 00 00 f1 ff |................|
00000300 0d 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 |................|
00000310 2d 00 00 00 10 00 02 00 00 00 00 00 00 00 00 00 |-...............|
00000320 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 |................|
00000330 00 68 65 6c 6c 6f 5f 77 6f 72 6c 64 2e 61 73 6d |.hello_world.asm|
00000340 00 68 65 6c 6c 6f 5f 77 6f 72 6c 64 00 68 65 6c |.hello_world.hel|
00000350 6c 6f 5f 77 6f 72 6c 64 5f 6c 65 6e 00 5f 73 74 |lo_world_len._st|
00000360 61 72 74 00 00 00 00 00 00 00 00 00 00 00 00 00 |art.............|
00000370 0c 00 00 00 00 00 00 00 01 00 00 00 02 00 00 00 |................|
00000380 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 00 |................|
00000390Array of
Elf64_Shdr structs.Each entry contains metadata about a given section.
e_shoff of the ELF header gives the starting position, 0x40 here.e_shentsize and e_shnum from the ELF header say that we have 7 entries, each 0x40 bytes long.So the table takes bytes from 0x40 to
0x40 + 7 + 0x40 - 1 = 0x1FF.Some section names are reserved for certain section types: www.sco.com/developers/gabi/2003-12-17/ch4.sheader.html#special_sections e.g.
.text requires a SHT_PROGBITS type and SHF_ALLOC + SHF_EXECINSTRRunning:outputs:
readelf -S hello_world.oThere are 7 section headers, starting at offset 0x40:
Section Headers:
[Nr] Name Type Address Offset
Size EntSize Flags Link Info Align
[ 0] NULL 0000000000000000 00000000
0000000000000000 0000000000000000 0 0 0
[ 1] .data PROGBITS 0000000000000000 00000200
000000000000000d 0000000000000000 WA 0 0 4
[ 2] .text PROGBITS 0000000000000000 00000210
0000000000000027 0000000000000000 AX 0 0 16
[ 3] .shstrtab STRTAB 0000000000000000 00000240
0000000000000032 0000000000000000 0 0 1
[ 4] .symtab SYMTAB 0000000000000000 00000280
00000000000000a8 0000000000000018 5 6 4
[ 5] .strtab STRTAB 0000000000000000 00000330
0000000000000034 0000000000000000 0 0 1
[ 6] .rela.text RELA 0000000000000000 00000370
0000000000000018 0000000000000018 4 2 4
Key to Flags:
W (write), A (alloc), X (execute), M (merge), S (strings), l (large)
I (info), L (link order), G (group), T (TLS), E (exclude), x (unknown)
O (extra OS processing required) o (OS specific), p (processor specific)The
struct represented by each entry is:typedef struct {
Elf64_Word sh_name;
Elf64_Word sh_type;
Elf64_Xword sh_flags;
Elf64_Addr sh_addr;
Elf64_Off sh_offset;
Elf64_Xword sh_size;
Elf64_Word sh_link;
Elf64_Word sh_info;
Elf64_Xword sh_addralign;
Elf64_Xword sh_entsize;
} Elf64_Shdr;Experiments to measure it:
The 2019 redefinition of the SI base units defines it precisely and uses it as a measure of charge: en.wikipedia.org/wiki/2019_redefinition_of_the_SI_base_units#Ampere
E. Coli Whole Cell Model by Covert Lab by 
Ciro Santilli 35 Updated 2025-04-05 +Created 1970-01-01
Ciro Santilli 35 Updated 2025-04-05 +Created 1970-01-01github.com/CovertLab/WholeCellEcoliRelease is a whole cell simulation model created by Covert Lab and other collaborators.
The project is written in Python, hurray!
But according to te README, it seems to be the use a code drop model with on-request access to master. Ciro Santilli asked at rationale on GitHub discussion, and they confirmed as expected that it is to:
- to prevent their publication ideas from being stolen. Who would steal publication ideas with public proof in an issue tracker without crediting original authors? Academia is broken. Academia should be the most open form of knowledge sharing. But instead we get this silly competition for publication points.
- to prevent noise from non-collaborators. But they only get like 2 issues as year on such a meganiche subject... Did you know that you can ignore people, and even block them if they are particularly annoying? Much more likely is that no one will every hear about your project and that it will die with its last graduate student slave.
The project is a followup to the earlier M. genitalium whole cell model by Covert lab which modelled Mycoplasma genitalium. E. Coli has 8x more genes (500 vs 4k), but it the undisputed bacterial model organism and as such has been studied much more thoroughly. It also reproduces faster than Mycoplasma (20 minutes vs a few hours), which is a huge advantages for validation/exploratory experiments.
The project has a partial dependency on the proprietary optimization software CPLEX which is freeware, for students, not sure what it is used for exactly, from the comment in the
requirements.txt the dependency is only partial.This project makes Ciro Santilli think of the E. Coli as an optimization problem. Given such external nutrient/temperature condition, which DNA sequence makes the cell grow the fastest? Balancing metabolites feels like designing a Factorio speedrun.
There is one major thing missing thing in the current model: promoters/transcription factor interactions are not modelled due to lack/low quality of experimental data: github.com/CovertLab/WholeCellEcoliRelease/issues/21. They just have a magic direct "transcription factor to gene" relationship, encoded at reconstruction/ecoli/flat/foldChanges.tsv in terms of type "if this is present, such protein is expressed 10x more". Transcription units are not implemented at all it appears.
Everything in this section refers to version 7e4cc9e57de76752df0f4e32eca95fb653ea64e4, the code drop from November 2020, and was tested on Ubuntu 21.04 with a docker install of
docker.pkg.github.com/covertlab/wholecellecolirelease/wcm-full with image id 502c3e604265, unless otherwise noted.Have a look at some interesting examples under nodejs/sequelize/raw/many_to_many.js.
Company co-founded by Scott Hassan, early Google programmer at Stanford University, and Carl Victor Page, Jr., Larry Page's older brother.
They were an email list management website, and became Yahoo! Groups after the acquisition.
The company was sold to Yahoo! in August 2000 for $432m and became Yahoo! Groups. They managed to miraculously dodge the Dot-com bubble, which mostly poppet in 2021. After the acquisition, Yahoo started to redirect them to: groups.yahoo.com as can be seen on the Wayback Machine: web.archive.org/web/20000401000000*/egroups.com The first archive of groups.yahoo.com is from February 2001: web.archive.org/web/20010202055100/http://groups.yahoo.com/ and it unsurprisingly looks basically exactly like eGroups.
eGroups logo
. From the earliest archive of their "about" page: web.archive.org/web/19991004062653/http://www.egroups.com/info/top.html in 1999.Unlike SARS-CoV-2 non-structural protein, these are not needed for test tube reproduction. They must therefore be for host modulation.
Uses Redux, while reactjs/react-rails appears to do that more manually
Lots of focus on Heroku deployability, which is fantastic: shakacode.gitbooks.io/react-on-rails/content/docs/additional-reading/heroku-deployment.html
Live instance: www.reactrails.com/ with source at: github.com/shakacode/react-webpack-rails-tutorial Not the most advanced web-app (a gothinkster/realworld-level would be ideal). Also has clear dependency description, which is nice.
Trying at github.com/shakacode/react-webpack-rails-tutorial/tree/8e656f97d7a311bbe999ceceb9463b8479fef9e2 on Ubuntu 20.10. Got some failures: github.com/shakacode/react-webpack-rails-tutorial/issues/488 Finally got a version of it working at: github.com/shakacode/react-webpack-rails-tutorial/issues/488#issuecomment-812506821
Oh, and the guy behind that project lives in Hawaii (Ciro Santilli's ideal city to live in), has an Asian-mixed son, and two Kinesis Advantage 2 keyboards as seen at twitter.com/railsonmaui/status/1377515748910755851, Ciro Santilli was jealous of him.
- stackoverflow.com/questions/1206872/go-to-previous-line-in-gdb/46996380#46996380
- stackoverflow.com/questions/1470434/how-does-reverse-debugging-work/53063242#53063242
- stackoverflow.com/questions/3649468/setting-breakpoint-in-gdb-where-the-function-returns/46116927#46116927
- stackoverflow.com/questions/27770896/how-to-debug-a-rare-deadlock/50073993#50073993
- stackoverflow.com/questions/522619/how-to-do-bidirectional-or-reverse-debugging-of-programs/50074106#50074106 link only, marked as duplicate of go to previous line
- softwareengineering.stackexchange.com/questions/181527/why-is-reverse-debugging-rarely-used
Framework built on top of React.
Officially recommended by React[ref]:
Recommended ToolchainsIf you’re building a server-rendered website with Node.js, try Next.js.
gothinkster/realworld blog example by Ciro Santilli: node Express Sequelize Next.js realworld example app.
Basically what this does is to get server-side rendering just working by React, including hydration, which is a good thing.
Next.js sends the first pre-rendered HTML page along with the JavaScript code. Then, JavaScript page switches just load the API data.
Next.js does this nicely by forcing you to provide page data in a serialized JSON format, even when rendering server-side (e.g. the return value of
getServerSideProps). This way, it is also able to provide either the full HTML, or just the JSON.Some general downsides:
- it does feel like they don't document deployment very well however, especially non-Vercel options, which is the company behind Next.js. I'm unable to find how to use a non Vercel CDN with ISR supposing that is possible.
- Next.js is very opinionated, and like any opinionated library it is sometimes hard to know why something is/isn't happening, and sometimes it is hard/impossible to do what you want with it unless they add support. They have done good progress, but even as of 2022, some aspects just feel so immature, some major-looking use cases are not very well done.
In theory, Next.js could be the "ultimate frontend framework". It does have a lot of development difficulties that need to be ironed out, but the general concepts, and things it tries to integrate, including e.g. webpack, TypeScript, etc. are good. Maybe the question is when will someone put it together with an amazing backend library and dominate and finally put an end to the infinite number of Js Frameworks!
In-tree examples at: github.com/vercel/next.js/tree/canary/examples
In order to offer its amazing features, Next.js is also extremely opinionated, which means that if something wasn't designed to be possible, it basically isn't.
No prerender with custom server? It forces you to write your API with next as well? Or does it mean something else?
TODO can it statically generate pages that are created at runtime? E.g. if I create a new blog post, will it automatically upload a static page? It seems that yes, and that this is exactly what Incremental Static Regeneration means:However, Ciro can't find any mention of how to specify where the pages are uploaded to... this is pat of the non-Vercel deployment problem.
- github.com/vercel/next.js/discussions/25410
- vercel.com/docs/next.js/incremental-static-regeneration
- github.com/vercel/next.js/discussions/17711
- www.reddit.com/r/nextjs/comments/mvvhym/a_complete_guide_to_incremental_static/
- github.com/vercel/next.js/discussions/11552#discussioncomment-115595
- stackoverflow.com/questions/62105756/how-to-use-aws-with-next-js
- github.com/vercel/next.js/discussions/17080
- github.com/vercel/next.js/discussions/16852
Can't ISR prerenter by URL query parameters:
That plus the requirement to have one page per file under
pages/ leads to a lot of useless duplication, because then you are forced to place the URL parameters on the pathnames."Module not found: Can't resolve 'fs'" Hell. The main reason this happens seems to be the that in a higher order component, webpack can't determine if callbacks use the require or not to remove it from frontend code. Fully investigated and solved at:
Overviews:
- www.reddit.com/r/reactjs/comments/8evy5d/what_are_the_downsides_to_nextjs/ 2017 What are the downsides to Next.js?
Examples under python/sklearn
. .venv/bin/activate
pip install sklearn matplotlib seabornA more photon-specific version of the Bloch sphere.
In it, each of the six sides has a clear and simple to understand photon polarization state, either of:
- left/right
- diagonal up/diagonal down
- rotation clockwise/counterclockwise
The sphere clearly suggests for example that a rotational or diagonal polarizations are the combination of left/right with the correct phase. This is clearly explained at: Video "Quantum Mechanics 9b - Photon Spin and Schrodinger's Cat II by ViaScience (2013)".
There are unlisted articles, also show them or only show them.