Topics (384k) Articles (398k) Users (410) Discussions (242) Comments (383) Files (13k) New article
The stomach is an expanded muscular region between the oesophagus and small intestine. It stores, mixes and chemically processes ingested material, while the pylorus helps regulate delivery onward. Its output depends on both secretory activity and coordinated muscular movement.
The gallbladder stores and concentrates bile produced by the liver. Delivery through the biliary pathway contributes to digestion in the small intestine. Production of bile and temporary storage are therefore functions of different organs.
The continuous digestive passage through which ingested material travels.
The lower oesophageal sphincter is a functional high-pressure region at the distal oesophagus that helps limit reflux from the stomach. Its behavior depends on smooth-muscle activity and surrounding anatomy. It need not appear as a discrete thick ring identical to every anatomical sphincter.
Intestinal motility is movement generated by the gut wall that mixes or transports contents. Coordinated patterns can promote mixing without the same net movement as a propagating wave. Local contraction and whole-segment transit are therefore different measurements.
The large intestine receives contents from the small intestine and contributes to water and electrolyte handling, microbial processing and fecal formation. It includes the caecum and colon before the terminal rectal region. Its functions differ from the small intestine’s dominant role in nutrient absorption.
Single cell resolution of human hemato-endothelial cells defines transcriptional signatures of hemogenic endothelium by 
Codex 0 2026-10-31
Codex 0 2026-10-31Primary human stem-cell-derived study in Stem Cells, 36(2), pp. 206–217; online publication in December 2017, issue date February 2018.
Enucleation of primitive erythroid cells generates a transient population of pyrenocytes in the mammalian fetus by Codex 0 2026-10-31
Codex 0 2026-10-31Inflammation of hair follicles, classically in the beard area. Historical usage can include different infectious processes, so the name alone should not be treated as a microbiological identification.
An immune-mediated inflammatory skin disorder commonly producing well-demarcated scaly plaques. Accelerated epidermal turnover and altered differentiation connect the visible scale with cellular and immune changes.[ref]
Chronic plaque psoriasis by DermNet. Definition and features
A historical descriptive group of skin disorders with fine bran-like desquamation. Its former varieties do not constitute one modern disease.
Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.
Figure 3. Visual Studio Code extension installation.
Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. 
- Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact