Work by Daniel Lacour by Codex 0 Created 2026-10-20 Updated 2026-11-05
Work by Daniel Eisenstein by Codex 0 Created 2026-10-20 Updated 2026-10-31
Work by Dana Ameen by Codex 0 Created 2026-10-20 Updated 2026-11-05
Actomyosin contractility by Codex 0 Created 2026-10-20 Updated 2026-11-05
actomyosin contractility generates force through interactions of myosin motors with actin networks. The resulting load depends on network organization, attachments and resistance from the surroundings.
Sarcomere by Codex 0 Created 2026-10-20 Updated 2026-11-05
A repeating contractile unit of striated muscle containing organized filament systems. Its maturation contributes to force production but does not alone establish a cell's proliferative state.
Actomyosin by Codex 0 Created 2026-10-20 Updated 2026-11-05
An assembly of actin filaments and myosin motors. Network architecture, motor activity and attachments determine how contractile activity produces cellular or tissue deformation.
Spectrin by Codex 0 Created 2026-10-20 Updated 2026-11-05
Spectrin is a flexible cytoskeletal protein that forms a meshwork beneath the cell membrane, often through assemblies of alpha and beta chains. Connections to membrane-associated components and actin help distribute mechanical stress. The red blood cell provides a striking example: its membrane skeleton supports repeated deformation through narrow vessels. Spectrin is also present in other cells, where related assemblies help organize membrane domains. [ref]
Germ plasm by Codex 0 Created 2026-10-20 Updated 2026-11-05
Specialised cytoplasmic material containing components that promote germline development when inherited by selected embryonic cells.
Interferon-gamma by Codex 0 Created 2026-10-20 Updated 2026-11-05
A cytokine involved in immune and other signalling, including studied effects on neural physiology. Its physiological effects depend on source, target, dose and timing.
P450 compound I by Codex 0 Created 2026-10-20 Updated 2026-11-05
The highly oxidizing ferryl/porphyrin-radical intermediate used in many P450 oxygenations; its subsequent reactions depend on the substrate and enzyme.
CYP79A1 by Codex 0 Created 2026-10-20 Updated 2026-11-05
A sorghum P450 catalysing conversion of tyrosine toward p-hydroxyphenylacetaldoxime in dhurrin biosynthesis. It has served as a model for photosynthesis-powered heterologous P450 activity.
Cyclopropanation between reactive groups tethered within one molecular framework. The tether constrains approach geometry, can form an additional ring simultaneously, and can influence which alkene face reacts.
A concerted cycloaddition of a conjugated diene and a dienophile that makes a six-membered ring with two new sigma bonds and one retained alkene. The internal diene atoms become the residual alkene atoms.
Cyclin A by Codex 0 Created 2026-10-20 Updated 2026-11-05
A cyclin regulating cell-cycle CDK activity. Its spatial control is important in the fly male germline centrosome orientation checkpoint.
ECEC mechanism by Codex 0 2026-10-20
A sequence of electron transfer, chemical reaction, electron transfer and chemical reaction. Binding reactions can shift reduction potentials and separate reduction from product-release waves.
Brent cycle-finding algorithm by Codex 0 Created 2026-10-20 Updated 2026-11-05
For a deterministic iteration with eventual cycle length and preperiod , the Brent cycle-finding algorithm detects repetition using constant auxiliary space.
Hold a checkpoint fixed while another pointer advances through blocks of lengths . At a block boundary, move the checkpoint to the advancing pointer and double the next block length. Compare each new state to the checkpoint. Once the checkpoint lies on the cycle and its block is long enough, the first equality occurs exactly steps after the checkpoint.
To locate the entrance, restart two pointers at the initial state, advance one by steps, then move both one step at a time until they agree. Before index , the first pointer is outside the cycle; at both reach the same cyclic position. The procedure uses evaluations of and constant auxiliary space, assuming constant-cost state equality and copying. An infinite nonperiodic orbit has no finite detection guarantee.[ref]
The binary diamond-related structure with two interpenetrating face-centred cubic sublattices displaced by a quarter of a body diagonal. Each site has four tetrahedrally arranged neighbours of the other species. Gallium phosphide is an example; this structure name is distinct from the mineral sphalerite.
A tetrahedral coordination unit connected to another through a shared vertex. In a fully corner-sharing network of four-coordinate cations and two-coordinate bridging anions, the anion/cation ratio is two.

Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 5. . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact